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pyridoxal isonicotinoyl hydrazone

Product Name
pyridoxal isonicotinoyl hydrazone
CAS No.
737-86-0
Chemical Name
pyridoxal isonicotinoyl hydrazone
Synonyms
NSC 77674;PIH - CAS 737-86-0 - Calbiochem;Pyridoxal isonicotinoyl hydrazine;PIH(Pyridoxal isonicotinoyl hydrazine);Pyridoxal isonicotinoyl hydrazone (PIH);inhibit,pyridoxal isonicotinoyl hydrazone,Inhibitor;N'-((3-Hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)isonicotinohydrazide;N'-((3-Hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)isonicotinohydrazide;4-Pyridinecarboxylic acid, 2-[[3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinyl]methylene]hydrazide
CBNumber
CB31370372
Molecular Formula
C14H14N4O3
Formula Weight
286.29
MOL File
737-86-0.mol
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pyridoxal isonicotinoyl hydrazone Property

Melting point:
261-262 °C (decomp)
Density 
1.35±0.1 g/cm3(Predicted)
storage temp. 
+2C to +8C
solubility 
DMF: 1 mg/ml; DMSO: 5 mg/ml; Ethanol: 0.5 mg/ml
form 
Yellow solid
pka
8.04±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
528110-M
Product name
PIH - CAS 737-86-0 - Calbiochem
Purity
A cell-permeable, non-toxic tridendate iron (Fe3+) chelator of the aroyl hydrazone class.
Packaging
528110-50MG
Price
$275
Updated
2024/03/01
Sigma-Aldrich
Product number
528110-M
Product name
PIH - CAS 737-86-0 - Calbiochem
Purity
A cell-permeable, non-toxic tridendate iron (Fe3+) chelator of the aroyl hydrazone class.
Packaging
50mg
Price
$210
Updated
2022/05/15
Cayman Chemical
Product number
19357
Product name
Pyridoxal isonicotinoyl hydrazone
Purity
≥99%
Packaging
50mg
Price
$141
Updated
2024/03/01
TRC
Product number
P991723
Product name
PyridoxalIsonicotinoylHydrazone
Packaging
100mg
Price
$335
Updated
2021/12/16
ApexBio Technology
Product number
B6060
Product name
Pyridoxalisonicotinoylhydrazone
Packaging
50mg
Price
$105
Updated
2021/12/16
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pyridoxal isonicotinoyl hydrazone Chemical Properties,Usage,Production

Uses

Pyridoxal Isonicotinoyl Hydrazone is a cell-permeable non-toxic iron chelator of the aroyl hydrazone class.

General Description

A cell-permeable, non-toxic tridendate iron (Fe3+) chelator of the aroyl hydrazone class. Even at low concentrations, highly effective in mobilizing Fe3+ from cells and preventing its uptake from transferrin, even at low concentrations. Exhibits similar specificity and binding affinity as Deferoxamine Mesylate (Cat. No. 252750) but has greater access to mitochondrial iron. Also useful for the management of iron overload disease in experimental models. Inhibits the induction of heme containing indoleamine 2,3-dioxygenase activity.

pyridoxal isonicotinoyl hydrazone Preparation Products And Raw materials

Raw materials

Preparation Products

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pyridoxal isonicotinoyl hydrazone Suppliers

China 31 United States 7 Global 38
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
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80
ShangHai Biochempartner Co.,Ltd
Tel
17754423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
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62
Chuzhou KeMail Chemical Technology Co., Ltd
Tel
0550-5196001 15000891977
Fax
0550-5196001
Email
wj520wjxby@126.com
Country
China
ProdList
1836
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55
Henan Alfachem Co.,Ltd.
Tel
0371-0371-55051623 18137891487
Fax
QQ：2853979817
Email
2853979817@qq.com
Country
China
ProdList
9976
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58
Jiangsu aikang biomedical research and development co., LTD
Tel
025-66110311 13155353615
Email
qzhang@aikonchem.com
Country
China
ProdList
15527
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58
Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471 +1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10523
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58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6393
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58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9414
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58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11289
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58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
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58

737-86-0, pyridoxal isonicotinoyl hydrazoneRelated Search:

pyridoxal isonicotinoyl hydrazone

  • Pyridoxal isonicotinoyl hydrazone (PIH)
  • NSC 77674
  • PIH(Pyridoxal isonicotinoyl hydrazine)
  • PIH - CAS 737-86-0 - Calbiochem
  • Pyridoxal isonicotinoyl hydrazine
  • 4-Pyridinecarboxylic acid, 2-[[3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinyl]methylene]hydrazide
  • N'-((3-Hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)isonicotinohydrazide
  • inhibit,pyridoxal isonicotinoyl hydrazone,Inhibitor
  • N'-((3-Hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)isonicotinohydrazide
  • 737-86-0