ChemicalBook > CAS DataBase List > 2-iodoestradiol
2-iodoestradiol
- Product Name
- 2-iodoestradiol
- CAS No.
- 24381-12-2
- Chemical Name
- 2-iodoestradiol
- Synonyms
- NSC671618;NSC-671618;NSC 671618;Estra-1,3,5(10)-triene-3,17-diol, 2-iodo-, (17β)-
- CBNumber
- CB31378929
- Molecular Formula
- C18H23IO2
- Formula Weight
- 398.28
- MOL File
- 24381-12-2.mol
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2-iodoestradiol Chemical Properties,Usage,Production
Uses
2-Iodoestradiol is a potent human sex hormone binding globulin (SHBG) ligand with a remarkably high affinity for SHBG. 2-Iodoestradiol exhibits competition for the same binding site as dihydrotestosterone in binding to human SHBG. The binding affinity constant of 2-Iodoestradiol at physiological pH and 37 degrees Celsius is 2.4 x 10(9) M-1, exceeding that for SHBG. 2-Iodoestradiol has been shown to bind to serum albumin, but with lower affinity. The radioisotope 125I-derivative of 2-Iodoestradiol has been used to study the binding properties of human SHBG, demonstrating its potential application in biological research[1].
References
[1] 2-Iodoestradiol binds with high affinity to human sex hormone binding globulin (SHBG)
2-iodoestradiol Preparation Products And Raw materials
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Preparation Products
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2-iodoestradiol Suppliers
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- +1-781-999-5354; +17819995354
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