setoclavine
- Product Name
- setoclavine
- CAS No.
- 519-12-0
- Chemical Name
- setoclavine
- Synonyms
- setoclavine;9,10-Didehydro-6,8-dimethylergolin-8α-ol;Ergolin-8-ol, 9,10-didehydro-6,8-dimethyl-, (8α)-
- CBNumber
- CB31387112
- Molecular Formula
- C16H18N2O
- Formula Weight
- 254.33
- MOL File
- 519-12-0.mol
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setoclavine Property
- Melting point:
- 216-222 °C (decomp)(Solv: ethyl ether (60-29-7))
- Boiling point:
- 473.6±45.0 °C(Predicted)
- Density
- 1.30±0.1 g/cm3(Predicted)
- pka
- 13.85±0.20(Predicted)
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setoclavine Chemical Properties,Usage,Production
Description
An ergot alkaloid from the mycelia of Claviceps purpurea, the base yields colourless prisms when crystallized from Me2CO or MeOH. It is dextrorotatory having [α]20D + 165° (c 0.3, EtOH) or + 174° (c 1.0, CHCI3)' The ultraviolet spectrum in EtOH exhibits two absorption maxima at 243 and 313 mJ.1. The alkaloid forms crystalline salts with mineral acids, e.g. the hydrochloride, m.p. > 300°C and the nitrate, m.p. > 300°C;[α]20D + 190° (c 0.5,50% aqueous EtOH). The nitrogen atoms are present as an imino and a methylimino group.
References
Hofmann et al., Helv. Chim. Acta, 40, 1358 (1957)
setoclavine Preparation Products And Raw materials
Raw materials
Preparation Products
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