AK 2123
- Product Name
- AK 2123
- CAS No.
- 104958-90-9
- Chemical Name
- AK 2123
- Synonyms
- AK 2123;Sanazole;N-(2-Methoxyethyl)-3-nitro-1H-1,2,4-triazole-1-acetamide
- CBNumber
- CB31389545
- Formula Weight
- 0
- MOL File
- 104958-90-9.mol
N-Bromosuccinimide Price
- Product number
- API0012463
- Product name
- SANAZOLE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.34
- Updated
- 2021/12/16
AK 2123 Chemical Properties,Usage,Production
Uses
Sanazole (AK-2123) is a hypoxic cell radiosensitizer. Sanazole enhances radiation-induced DNA strand breaks. In mouse fibroblast tumors, Sanazole increases nuclear condensation and fragmentation, as well as elevates caspase-3 activity, thereby enhancing radiation-induced apoptosis. These characteristics make Sanazole a promising candidate for research in tumor therapy[1][2].
References
[1] Rajagopalan, et al. Radiosensitizer Sanazole (AK-2123) enhances γ-radiation-induced Apoptosis in murine fibrosarcoma. Journal of radiation research 44.4 (2003): 359-365. DOI:10.1269/jrr.44.359
[2] García-Angulo, et al. "Intratumoral and parametrial infusion of a 3-nitrotriazole (AK-2123) in the radiotherapy of the uterine cervix cancer: stage II–III—preliminary positive results." International Journal of Radiation Oncology Biology Physics 22.3 (1992): 589-591. DOI:10.1016/0360-3016(92)90883-j
AK 2123 Preparation Products And Raw materials
Raw materials
Preparation Products
AK 2123 Suppliers
- Tel
- 15002134094
- marketing@targetmol.cn
- Country
- China
- ProdList
- 29423
- Advantage
- 58
- Tel
- +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 19962
- Advantage
- 58
- Tel
- +1-781-999-5354;
- support@targetmol.com
- Country
- United States
- ProdList
- 39035
- Advantage
- 58
- Tel
- +86-057181025280; +8617767106207
- Fax
- 0571-85806285
- sales@molcore.com
- Country
- China
- ProdList
- 49734
- Advantage
- 58