HYDROXYDIONESODIUM
- Product Name
- HYDROXYDIONESODIUM
- CAS No.
- 53-10-1
- Chemical Name
- HYDROXYDIONESODIUM
- Synonyms
- Viadril;Presuren;HYDROXYDION;HYDROXYDIONESODIUM;Hydroxidioni natrii succinas;Hidroxidiona succinato sodico;HYDROXYDIONESODIUMSUCCINATE USP/EP/BP;Hidroxidiona succinato sodico [inn-spanish];21-Hydroxypregnane-3,20-dione sodium hemisuccinate;Succinic acid 1-sodium 4-(3,20-dioxo-5β-pregnane-21-yl)
- CBNumber
- CB31406549
- Molecular Formula
- C25H35NaO6
- Formula Weight
- 454.54
- MOL File
- 53-10-1.mol
N-Bromosuccinimide Price
- Product number
- 177657
- Product name
- Hydroxydione sodium succinate
- Packaging
- 1g
- Price
- $195
- Updated
- 2021/12/16
- Product number
- API0016483
- Product name
- HYDROXYDIONE SODIUM
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.18
- Updated
- 2021/12/16
HYDROXYDIONESODIUM Chemical Properties,Usage,Production
Originator
Viadril,Pfizer,US,1957
Manufacturing Process
A solution of 20 g of desoxycorticosterone in 190 ml of absolute ethanol was
stirred in an atmosphere of hydrogen in the presence of 1.68 g of 25%
palladium on calcium carbonate catalyst. After 20 hours, approximately 1
molar equivalent of hydrogen had been absorbed and hydrogen uptake had
ceased. The catalyst was removed by filtration and the filtrate evaporated in
vacuo to yield 20 g of nearly pure product, MP 135°C to 140°C. The crude
product was demonstrated to be free of starting material by paper
chromatography. A highly purified product was obtained by recrystallization
from acetone-water with cooling in an ice bath, yield 14.5 g, MP 152°C to
154°C. The product was characterized by analysis and by absence of
ultraviolet absorption.
A solution of 14 g of 21-hydroxypregnane-3,20-dione and of 14 g of
recrystallized succinic anhydride in 140 ml of dry pyridine was allowed to
stand at room temperature for 18 hours, then cooled in an ice bath and
poured in a fine stream into 1.5 liters of ice water. Excess pyridine was
neutralized with 3N hydrochloric acid and the solution further diluted with 2
liters of ice water. The precipitated product was filtered, washed with water
and dried in vacuo at 50°C affording 18 g of solid MP 192°C to 195°C.
Recrystallization of a small sample afforded analytically pure material, MP
200°C.
Therapeutic Function
Anesthetic
HYDROXYDIONESODIUM Preparation Products And Raw materials
Raw materials
Preparation Products
HYDROXYDIONESODIUM Suppliers
- Tel
- +86-29-89586680 +86-15129568250
- 1026@dideu.com
- Country
- China
- ProdList
- 22883
- Advantage
- 58
View Lastest Price from HYDROXYDIONESODIUM manufacturers
- Product
- HYDROXYDIONESODIUMSUCCINATE
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-07-08