ALPHA-AMANITIN
- Product Name
- ALPHA-AMANITIN
- CAS No.
- 23109-05-9
- Chemical Name
- ALPHA-AMANITIN
- Synonyms
- Α-AMANITIN;α-Amanitin;A-AMANITIN;Aids004473;α-Amatoxin;Aids-004473;AMANITIN, A-;ALPHA-AMANTIN;ALPHA-AMANITIN;alpha-amatoxin
- CBNumber
- CB3142945
- Molecular Formula
- C39H54N10O14S
- Formula Weight
- 918.98
- MOL File
- 23109-05-9.mol
ALPHA-AMANITIN Property
- Melting point:
- 254-255 °C(lit.)
- alpha
- D20 +191°
- Boiling point:
- 1622.2±65.0 °C(Predicted)
- Density
- 1.1626 (rough estimate)
- refractive index
- 1.7400 (estimate)
- storage temp.
- −20°C
- solubility
- H2O: 1.0 mg/mL
- form
- powder
- pka
- 9.63±0.70(Predicted)
- color
- white to light yellow
- optical activity
- +19120 (H2O)
- Water Solubility
- Soluble to 5 mM in ethanol and to 5 mM in water
- Merck
- 13,370
- BRN
- 1071138
- InChIKey
- CIORWBWIBBPXCG-PWKRRBCNNA-N
Safety
- Hazard Codes
- T+
- Risk Statements
- 26/27/28-33-26/28
- Safety Statements
- 36/37/39-45-36/37-28
- RIDADR
- UN 3462 6.1/PG 2
- WGK Germany
- 3
- RTECS
- BD6195000
- F
- 8-10-18-21
- HazardClass
- 6.1(a)
- PackingGroup
- I
- HS Code
- 2934999090
- Hazardous Substances Data
- 23109-05-9(Hazardous Substances Data)
- Toxicity
- LD50 i.p. in albino mice: 0.1 mg/kg (Wieland, Wieland)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H300Fatal if swallowed
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P314Get medical advice/attention if you feel unwell.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- A2263
- Product name
- α-Amanitin
- Purity
- from Amanita phalloides, ≥90% (HPLC), powder
- Packaging
- 1mg
- Price
- $340
- Updated
- 2024/03/01
- Product number
- 17898
- Product name
- α-Amanitin
- Purity
- ≥90%
- Packaging
- 1mg
- Price
- $227
- Updated
- 2024/03/01
- Product number
- 4025
- Product name
- alpha-Amanitin
- Purity
- ≥95%(HPLC)
- Packaging
- 1
- Price
- $291
- Updated
- 2021/12/16
- Product number
- 257178
- Product name
- α-Amanitin
- Packaging
- 1mg
- Price
- $588
- Updated
- 2021/12/16
- Product number
- FA57619
- Product name
- a-Amanitin
- Packaging
- 5mg
- Price
- $800
- Updated
- 2021/12/16
ALPHA-AMANITIN Chemical Properties,Usage,Production
Uses
α-Amanitin has been used:
- for inducing transcriptional arrest in NT2 cells prior to immunofluorescence assay
- to induce nephrotoxicity in mice renal tissues
- to induce and analyse genotoxicity in mice bone marrow cells by cell viability assay, comet assay and chromosomal aberration assay
Biological Activity
α-amanitin, the most deleterious toxin of a. phalloides to humans, inhibits rna polymerase ii (rnapii), causing hepatic and renal failure.
Biochem/physiol Actions
The major toxic constituent of the mushroom, Amanita phalloides, inhibits eukaryotic RNA polymerase II and III, but does not inhibit RNA polymerase I or bacterial RNA polymerase. Inhibits mammalian protein synthesis.
storage
Store at -20°C
ALPHA-AMANITIN Preparation Products And Raw materials
Raw materials
Preparation Products
ALPHA-AMANITIN Suppliers
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- Country
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View Lastest Price from ALPHA-AMANITIN manufacturers
- Product
- α-Amanitin 23109-05-9
- Price
- US $60.00-45.00/mg
- Min. Order
- 1mg
- Purity
- 99.96%
- Supply Ability
- 1kg
- Release date
- 2023-03-14
- Product
- alpha-Amanitin 23109-05-9
- Price
- US $9.00-70.00/g
- Min. Order
- 10g
- Purity
- 99%
- Supply Ability
- 10 tons
- Release date
- 2024-03-27
- Product
- α-Amanitin 23109-05-9
- Price
- US $100.00/drum
- Min. Order
- 1drum
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2023-09-05