ChemicalBook > CAS DataBase List > Balaglitazone

Balaglitazone

Product Name: Balaglitazone
CAS No.: 199113-98-9
Chemical Name: Balaglitazone
Synonyms: Nn2344;Drf-2593;Drf 2593;Balaglitazone;Unii-4m1609828o;Balaglitazone [inn];DRF-2593;NN-2344;DRF2593;NN2344;DRF 2593;NN 2344;5-[[4-[(3-methyl-4-oxoquinazolin-2-yl)methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione;(+/-)-5-(p-((3,4-Dihydro-3-methyl-4-oxo-2-quinazolinyl)methoxy)benzyl)-2,4-thiazolidinedione;5-[[4-[(3,4-dihydro-3-methyl-4-oxo-2-quinazolinyl)methoxy]phenyl]methyl]-2,4-Thiazolidinedione
CBNumber: CB31465782
Molecular Formula: C20H17N3O4S
Formula Weight: 395.43
MOL File: 199113-98-9.mol

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Balaglitazone Property

Density: 1.45±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: insoluble in H2O; ≥15.45 mg/mL in DMSO; ≥2.18 mg/mL in EtOH with gentle warming and ultrasonic
form: solid
pka: 6.33±0.50(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28866
Product name: Balaglitazone
Packaging: 1mg
Price: $48
Updated: 2024/03/01

Cayman Chemical

Product number: 28866
Product name: Balaglitazone
Packaging: 10mg
Price: $288
Updated: 2024/03/01

Cayman Chemical

Product number: 28866
Product name: Balaglitazone
Packaging: 5mg
Price: $192
Updated: 2024/03/01

Cayman Chemical

Product number: 28866
Product name: Balaglitazone
Packaging: 25mg
Price: $420
Updated: 2024/03/01

TRC

Product number: B115450
Product name: Balaglitazone
Packaging: 1mg
Price: $150
Updated: 2021/12/16

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Balaglitazone Chemical Properties,Usage,Production

Uses

Balaglitazone can be used in biological study of mediation of transcriptional regulatory network by Musa acuminata MaDREB transcription factors in fruit ripening.

in vivo

Balaglitazone (3 mg/kg, p.o.) shows antihyperglycaemic activity in fully diabetic and insulin resistant db/db mice, and is more potent than the full PPARγ agonist rosiglitazone^[1]. Balaglitazone (10 mg/kg, p.o.) suppresses overall glucose, decreases insulin levels, and increases bodyweight in male diet-induced obese rats, and such effects are equal to that of 30 mg/kg pioglitazone^[3].

target

PPARγ

IC 50

PPARγ: 351 nM (EC₅₀, Human PPARγ)

Balaglitazone Preparation Products And Raw materials

Raw materials

Preparation Products

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199113-98-9, BalaglitazoneRelated Search:

Pioglitazone Pioglitazone hydrochloride Gliquidone Balaglitazone

Balaglitazone

2,4-Thiazolidinedione,5-[[4-[(3,4-dihydro-3-methyl-4-oxo-2-quinazolinyl) methoxy]phenyl]methyl]-

(+/-)-5-(p-((3,4-Dihydro-3-methyl-4-oxo-2-quinazolinyl)methoxy)benzyl)-2,4-thiazolidinedione

Balaglitazone [inn]

Drf 2593

Drf-2593

Nn2344

Unii-4m1609828o

5-[[4-[[3-Methyl-4-oxo-3,4-dihydro-2-quinazolinyl]methoxy]phenyl]methyl]thiazolidine-2,4-dione

5-[[4-[(3,4-dihydro-3-methyl-4-oxo-2-quinazolinyl)methoxy]phenyl]methyl]-2,4-Thiazolidinedione

DRF-2593;NN-2344;DRF2593;NN2344;DRF 2593;NN 2344

5-[[4-[(3-methyl-4-oxoquinazolin-2-yl)methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione

199113-98-9

APIs