ChemicalBook > CAS DataBase List > Neticonazole Hydrochloride

Neticonazole Hydrochloride

Product Name
Neticonazole Hydrochloride
CAS No.
130773-02-3
Chemical Name
Neticonazole Hydrochloride
Synonyms
SS-717;Atolant;Neticonazole hydrochloride;1-[2-methylsulfanyl-1-(2-pentoxyphenyl)ethenyl]imidazole hydrochloride;1-[(E)-2-methylsulfanyl-1-(2-pentoxyphenyl)ethenyl]imidazole,hydrochloride;(E)-1-(2-(Methylthio)-1-(2-(pentyloxy)phenyl)vinyl)-1H-imidazole hydrochloride;long-acting,colorectal,Neticonazole,antifungal,Neticonazole Hydrochloride,Imidazole,anti-cancer,nSMase2,Fungal,secretion,Inhibitor,p-ERK,anti-infection,inhibit,exosome
CBNumber
CB31480006
Molecular Formula
C17H23ClN2OS
Formula Weight
338.9
MOL File
130773-02-3.mol
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Neticonazole Hydrochloride Property

Melting point:
145-147°
storage temp. 
Store at -20°C
solubility 
DMSO: 250 mg/mL (737.68 mM)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0099200
Product name
Neticonazole(hydrochloride)
Purity
98.58%
Packaging
25mg
Price
$75
Updated
2021/12/16
ChemScene
Product number
CS-0099200
Product name
Neticonazole(hydrochloride)
Purity
98.58%
Packaging
50mg
Price
$135
Updated
2021/12/16
ChemScene
Product number
CS-0099200
Product name
Neticonazole(hydrochloride)
Purity
98.58%
Packaging
100mg
Price
$220
Updated
2021/12/16
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Neticonazole Hydrochloride Chemical Properties,Usage,Production

Description

Neticonazole hydrochloride is a novel imidazole antifungal agent introduced for the treatment of infections caused by Candida species. One percent neticonazole cream oncedaily application has been reported to be effective in treating patients with tinea pedis, tinea corporis, tinea cruris, intertrigo-type candidiasis, erosio interdigitalis and tinea versicolor. Compared with other agents of the azole class, neticonazole has the most potent activity against a variety of fungi, including the dermatophytes and pathogenic yeasts. It also has activity against Gram-positive, but not Gram-negative bacteria.

Originator

SS Pharmaceutical (Japan )

Definition

ChEBI: Neticonazole hydrochloride is a hydrochloride resulting from the formal reaction of equimolar amounts of neticonazole and hydrogen chloride. An inhibitor of P450-dependent C-14alpha-demethylation of lanosterol (preventing conversion to ergosterol and inhibiting cell wall synthesis in fungi), it is used in Japan as an antifungal drug for the treatment of superficial skin infections. It has a role as an antifungal drug and an EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor. It is a hydrochloride, an imidazole antifungal drug and a conazole antifungal drug. It contains a neticonazole(1+).

brand name

Atolant

Hazard

Moderately toxic by ingestion.

Neticonazole Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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130773-02-3, Neticonazole HydrochlorideRelated Search:


  • 1-[2-methylsulfanyl-1-(2-pentoxyphenyl)ethenyl]imidazole hydrochloride
  • Atolant
  • Neticonazole hydrochloride
  • SS-717
  • 1-[(E)-2-methylsulfanyl-1-(2-pentoxyphenyl)ethenyl]imidazole,hydrochloride
  • long-acting,colorectal,Neticonazole,antifungal,Neticonazole Hydrochloride,Imidazole,anti-cancer,nSMase2,Fungal,secretion,Inhibitor,p-ERK,anti-infection,inhibit,exosome
  • (E)-1-(2-(Methylthio)-1-(2-(pentyloxy)phenyl)vinyl)-1H-imidazole hydrochloride
  • 130773-02-3
  • C17H22N2OSHCl
  • C17H23ClN2OS