ChemicalBook > CAS DataBase List > Neticonazole Hydrochloride
Neticonazole Hydrochloride
- Product Name
- Neticonazole Hydrochloride
- CAS No.
- 130773-02-3
- Chemical Name
- Neticonazole Hydrochloride
- Synonyms
- SS-717;Atolant;Neticonazole hydrochloride;1-[2-methylsulfanyl-1-(2-pentoxyphenyl)ethenyl]imidazole hydrochloride;1-[(E)-2-methylsulfanyl-1-(2-pentoxyphenyl)ethenyl]imidazole,hydrochloride;(E)-1-(2-(Methylthio)-1-(2-(pentyloxy)phenyl)vinyl)-1H-imidazole hydrochloride;long-acting,colorectal,Neticonazole,antifungal,Neticonazole Hydrochloride,Imidazole,anti-cancer,nSMase2,Fungal,secretion,Inhibitor,p-ERK,anti-infection,inhibit,exosome
- CBNumber
- CB31480006
- Molecular Formula
- C17H23ClN2OS
- Formula Weight
- 338.9
- MOL File
- 130773-02-3.mol
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Neticonazole Hydrochloride Property
- Melting point:
- 145-147°
- storage temp.
- Store at -20°C
- solubility
- DMSO: 250 mg/mL (737.68 mM)
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0099200
- Product name
- Neticonazole(hydrochloride)
- Purity
- 98.58%
- Packaging
- 25mg
- Price
- $75
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0099200
- Product name
- Neticonazole(hydrochloride)
- Purity
- 98.58%
- Packaging
- 50mg
- Price
- $135
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0099200
- Product name
- Neticonazole(hydrochloride)
- Purity
- 98.58%
- Packaging
- 100mg
- Price
- $220
- Updated
- 2021/12/16
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Neticonazole Hydrochloride Chemical Properties,Usage,Production
Description
Neticonazole hydrochloride is a novel imidazole antifungal agent introduced for the treatment of infections caused by Candida species. One percent neticonazole cream oncedaily application has been reported to be effective in treating patients with tinea pedis, tinea corporis, tinea cruris, intertrigo-type candidiasis, erosio interdigitalis and tinea versicolor. Compared with other agents of the azole class, neticonazole has the most potent activity against a variety of fungi, including the dermatophytes and pathogenic yeasts. It also has activity against Gram-positive, but not Gram-negative bacteria.
Originator
SS Pharmaceutical (Japan )
Definition
ChEBI: Neticonazole hydrochloride is a hydrochloride resulting from the formal reaction of equimolar amounts of neticonazole and hydrogen chloride. An inhibitor of P450-dependent C-14alpha-demethylation of lanosterol (preventing conversion to ergosterol and inhibiting cell wall synthesis in fungi), it is used in Japan as an antifungal drug for the treatment of superficial skin infections. It has a role as an antifungal drug and an EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor. It is a hydrochloride, an imidazole antifungal drug and a conazole antifungal drug. It contains a neticonazole(1+).
brand name
Atolant
Hazard
Moderately toxic by ingestion.
Neticonazole Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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