1,5-DIBROMO-2,4-DIFLUOROBENZENE
- Product Name
- 1,5-DIBROMO-2,4-DIFLUOROBENZENE
- CAS No.
- 28342-75-8
- Chemical Name
- 1,5-DIBROMO-2,4-DIFLUOROBENZENE
- Synonyms
- 1.3-Dibrom-4.6-difluorben;1.3-Dibrom-4.6-difluorbenzol;2,4-Difluoro-1,5-dibromobenzene;1,3-DibroMo-4,6-difluorobenzene;1,5-DIBROMO-2,4-DIFLUOROBENZENE;Benzene, 1,5-dibromo-2,4-difluoro-;1,5-Dibromo-2,4-difluorobenzene，98%;1,5-Dibromo-2,4-difluorobenzene 98%
- CBNumber
- CB31496940
- Molecular Formula
- C6H2Br2F2
- Formula Weight
- 271.88
- MOL File
- 28342-75-8.mol
1,5-DIBROMO-2,4-DIFLUOROBENZENE Property
- Melting point:
- 29.0 to 33.0 °C
- Boiling point:
- 100℃ (25 Torr)
- Density
- 2.087±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- form
- powder to lump
- color
- White to Almost white
- InChI
- InChI=1S/C6H2Br2F2/c7-3-1-4(8)6(10)2-5(3)9/h1-2H
- InChIKey
- PPUZKAPOPPRMFE-UHFFFAOYSA-N
- SMILES
- C1(Br)=CC(Br)=C(F)C=C1F
Safety
- HS Code
- 2903998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- D5259
- Product name
- 1,5-Dibromo-2,4-difluorobenzene
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $35
- Updated
- 2025/07/31
- Product number
- D425388
- Product name
- 1,5-Dibromo-2,4-difluorobenzene
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- Y5121
- Product name
- 1,3-Dibromo-4,6-difluorobenzene
- Packaging
- 10g
- Price
- $94
- Updated
- 2021/12/16
- Product number
- 1600-B-28
- Product name
- 1,5-Dibromo-2,4-difluorobenzene
- Purity
- 98%
- Packaging
- 25g
- Price
- $125
- Updated
- 2021/12/16
- Product number
- PC9091
- Product name
- 1,5-Dibromo-2,4-difluorobenzene
- Purity
- 98%
- Packaging
- 100g
- Price
- $275
- Updated
- 2021/12/16
1,5-DIBROMO-2,4-DIFLUOROBENZENE Chemical Properties,Usage,Production
Synthesis
348-57-2
28342-75-8
General procedure for the synthesis of 1,5-dibromo-2,4-difluorobenzene from 2,4-difluorobromobenzene: Iron powder (3.15 g, 56 mmol) was added to a solution of 1-bromo-2,4-difluorobenzene (19.3 mL, 171 mmol) in dichloromethane (100 mL). A dichloromethane (25 mL) solution of bromine (11 mL, 214 mmol) was slowly added dropwise to the stirred suspension over 30 minutes. The reaction mixture was stirred overnight at room temperature. Subsequently, the reaction mixture was slowly poured into saturated aqueous sodium thiosulfate solution (200 mL) and stirring was continued for 30 minutes at room temperature. The reaction mixture was extracted with dichloromethane (3 x 80 mL). The organic phases were combined, washed with brine, dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give 1,5-dibromo-2,4-difluorobenzene (40 g, 86% yield) as a brown oil.1H NMR (500 MHz, chloroform-d) δ 7.79 (t, J = 7.0 Hz, 1H), 7.00 (t, J = 8.2 Hz, 1H).
References
[1] Journal of Organic Chemistry, 2004, vol. 69, # 6, p. 1967 - 1971
[2] Patent: WO2012/162334, 2012, A1. Location in patent: Page/Page column 38
[3] Patent: WO2014/98831, 2014, A1. Location in patent: Page/Page column 26; 27
[4] Nucleosides, Nucleotides and Nucleic Acids, 2001, vol. 20, # 1-2, p. 11 - 40
[5] Patent: EP1961743, 2008, A1. Location in patent: Page/Page column 19
1,5-DIBROMO-2,4-DIFLUOROBENZENE Preparation Products And Raw materials
Raw materials
Preparation Products
1,5-DIBROMO-2,4-DIFLUOROBENZENE Suppliers
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View Lastest Price from 1,5-DIBROMO-2,4-DIFLUOROBENZENE manufacturers
- Product
- 1,5-DIBROMO-2,4-DIFLUOROBENZENE 28342-75-8
- Price
- US $50.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-22
- Product
- 1,5-DIBROMO-2,4-DIFLUOROBENZENE 28342-75-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-12