2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL
- Product Name
- 2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL
- CAS No.
- 349-67-7
- Chemical Name
- 2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL
- Synonyms
- 2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL;Phenol, 2-methoxy-5-(trifluoromethyl)-
- CBNumber
- CB31499815
- Molecular Formula
- C8H7F3O2
- Formula Weight
- 192.14
- MOL File
- 349-67-7.mol
2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL Property
- Boiling point:
- 104-105 °C(Press: 12 Torr)
- Density
- 1.321±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 8.97±0.10(Predicted)
- Appearance
- Colorless to light yellow Liquid
Safety
- HS Code
- 2907199090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M332240
- Product name
- 2-Methoxy-5-(trifluoromethyl)phenol
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- HCH0357944
- Product name
- 2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $376.95
- Updated
- 2021/12/16
- Product number
- CM183650
- Product name
- 2-methoxy-5-(trifluoromethyl)phenol
- Purity
- 98%
- Packaging
- 1g
- Price
- $464
- Updated
- 2021/12/16
- Product number
- 349677
- Product name
- 2-Methoxy-5-(trifluoromethyl)phenol
- Packaging
- 250mg
- Price
- $489.6
- Updated
- 2021/12/16
- Product number
- CD12080373
- Product name
- 2-Methoxy-5-(trifluoromethyl)phenol
- Purity
- 98%
- Packaging
- 1g
- Price
- $491
- Updated
- 2021/12/16
2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL Chemical Properties,Usage,Production
Synthesis
240139-82-6
349-67-7
The general procedure for the synthesis of 2-methoxy-5-trifluoromethylphenol from 2-methoxy-5-trifluoromethylphenylboronic acid was as follows: to a 100 mL round bottom flask was added [2-methoxy-5-(trifluoromethyl)phenyl]boronic acid (300 mg, 1.36 mmol, 1.00 eq.), ethanol (15 mL), and 30% hydrogen peroxide aqueous solution (2 mL). The reaction mixture was stirred at 80°C for 2 hours. Upon completion of the reaction, the mixture was concentrated under reduced pressure. Subsequently, water was added to dilute the reaction mixture. The mixture was washed with aqueous sodium sulfite and the aqueous layer was extracted with ethyl acetate and the organic layers were combined. The organic layer was washed with saturated brine, dried over anhydrous sodium sulfate and finally concentrated under reduced pressure to give 250 mg (95% yield) of 2-methoxy-5-(trifluoromethyl)phenol as a colorless oil.
References
[1] Patent: WO2015/130957, 2015, A1. Location in patent: Page/Page column 85
[2] Journal of Medicinal Chemistry, 2004, vol. 47, # 12, p. 3089 - 3104
2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL Preparation Products And Raw materials
Raw materials
Preparation Products
2-METHOXY-5-(TRIFLUOROMETHYL)PHENOL Suppliers
- Tel
- --
- Fax
- --
- info@chemsworth.com
- Country
- India
- ProdList
- 6700
- Advantage
- 30
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58