ChemicalBook > CAS DataBase List > 2-(4-BROMOPHENYL)-PROPANEDIOIC ACID, 1,3-MDIETHYL ESTER

2-(4-BROMOPHENYL)-PROPANEDIOIC ACID, 1,3-MDIETHYL ESTER

Product Name
2-(4-BROMOPHENYL)-PROPANEDIOIC ACID, 1,3-MDIETHYL ESTER
CAS No.
149506-35-4
Chemical Name
2-(4-BROMOPHENYL)-PROPANEDIOIC ACID, 1,3-MDIETHYL ESTER
Synonyms
Macitentan Impurity 24;Macitentan Impurity 24 CRS;DiMethyl (4-BroMophenyl)-Malonate;diMethyl 2-(4-broMophenyl)Malonate;2-(4-Bromophenyl)-propanedioic acid;dimethyl 2-(4-bromophenyl)malonaAte;dimethyl 2-(4-bromophenyl)propanedioate;1,3-dimethyl 2-(4-bromophenyl)propanedioate;2-(4-Bromophenyl)malonic acid dimethyl ester;2-(4-Bromophenyl)-malonic acid 1,3-dimethyl ester
CBNumber
CB31502070
Molecular Formula
C11H11BrO4
Formula Weight
287.11
MOL File
149506-35-4.mol
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2-(4-BROMOPHENYL)-PROPANEDIOIC ACID, 1,3-MDIETHYL ESTER Property

Boiling point:
330.0±27.0 °C(Predicted)
Density 
1.467±0.06 g/cm3(Predicted)
pka
11.03±0.46(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
D464850
Product name
Dimethyl(4-Bromophenyl)malonate
Packaging
5g
Price
$1100
Updated
2021/12/16
ChemScene
Product number
CS-M1489
Product name
Propanedioicacid,2-(4-bromophenyl)-,1,3-dimethylester
Packaging
10g
Price
$760
Updated
2021/12/16
AK Scientific
Product number
1695AQ
Product name
1,3-dimethyl2-(4-bromophenyl)propanedioate
Packaging
1g
Price
$794
Updated
2021/12/16
ChemScene
Product number
CS-M1489
Product name
Propanedioicacid,2-(4-bromophenyl)-,1,3-dimethylester
Packaging
100mg
Price
$66
Updated
2021/12/16
ChemScene
Product number
CS-M1489
Product name
Propanedioicacid,2-(4-bromophenyl)-,1,3-dimethylester
Packaging
250mg
Price
$105
Updated
2021/12/16
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2-(4-BROMOPHENYL)-PROPANEDIOIC ACID, 1,3-MDIETHYL ESTER Chemical Properties,Usage,Production

Uses

Dimethyl (4-Bromophenyl)malonate is a useful synthetic intermediate in the synthesis of Macitentan (M105005); an orally active, potent dual endothelin receptor antagonist used for pulmonary arterial hypertension.

2-(4-BROMOPHENYL)-PROPANEDIOIC ACID, 1,3-MDIETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(4-BROMOPHENYL)-PROPANEDIOIC ACID, 1,3-MDIETHYL ESTER Suppliers

China 92 India 4 United Kingdom 1 United States 4 Global 101
Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4381
Advantage
58
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View Lastest Price from 2-(4-BROMOPHENYL)-PROPANEDIOIC ACID, 1,3-MDIETHYL ESTER manufacturers

Career Henan Chemical Co
Product
2-(4-BROMOPHENYL)-PROPANEDIOIC ACID, 1,3-MDIETHYL ESTER 149506-35-4
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-09

149506-35-4, 2-(4-BROMOPHENYL)-PROPANEDIOIC ACID, 1,3-MDIETHYL ESTERRelated Search:

5-(4-Bromophenyl)-4,6-dichloropyrimidine Macitidine related impurities PropylsulfaMide CarbaMic acid, N-[(propylaMino)sulfonyl]-, phenylMethyl ester 4(1H)-PyriMidinone, 5-(4-broMophenyl)-6-hydroxy- N-Propylsulfuric diamide-sodium SulfaMide, N-propyl-,(potassiuM salt)(1:1) Macitentan impurity A 5-Bromo-2-chloropyrimidine macitentan NA Masitatin impurity 3 Macitidine impurity 5 Macitidine impurity 2 2-(4-BROMOPHENYL)MALONDIALDEHYDE 2-(4-BROMOPHENYL)-PROPANEDIOIC ACID, 1,3-DIETHYL ESTER 2-(4-BROMOPHENYL)-PROPANEDIOIC ACID, 1,3-MDIETHYL ESTER 2-(4-BROMOPHENYL)-PROPANEDIOIC ACID 1,3-BIS-T-BUTYL ESTER

  • 2-(4-BROMOPHENYL)-PROPANEDIOIC ACID, 1,3-MDIETHYL ESTER
  • diMethyl 2-(4-broMophenyl)Malonate
  • Propanedioic acid, 2-(4-broMophenyl)-, 1,3-diMethyl ester
  • DiMethyl (4-BroMophenyl)-Malonate
  • 2-(4-Bromophenyl)malonic acid dimethyl ester
  • 2-(4-Bromophenyl)-malonic acid 1,3-dimethyl ester
  • dimethyl 2-(4-bromophenyl)malonaAte
  • 1,3-dimethyl 2-(4-bromophenyl)propanedioate
  • dimethyl 2-(4-bromophenyl)propanedioate
  • Macitentan Impurity 24
  • 2-(4-Bromophenyl)-propanedioic acid
  • 2-(4-bromophenyl)-Propanedioic acid 1,3-dimethyl ester
  • Macitentan Impurity 24 CRS
  • 149506-35-4