6-(bromomethyl)quinoxaline
- Product Name
- 6-(bromomethyl)quinoxaline
- CAS No.
- 53967-21-8
- Chemical Name
- 6-(bromomethyl)quinoxaline
- Synonyms
- 6-(bromomethyl)quinoxaline;Quinoxaline, 6-(bromomethyl)-
- CBNumber
- CB31515812
- Molecular Formula
- C9H7BrN2
- Formula Weight
- 223.07
- MOL File
- 53967-21-8.mol
6-(bromomethyl)quinoxaline Property
- Boiling point:
- 325.7±27.0 °C(Predicted)
- Density
- 1.599±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 0.52±0.30(Predicted)
- Appearance
- Yellow to brown Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- FB144127
- Product name
- 6-(Bromomethyl)quinoxaline
- Packaging
- 100mg
- Price
- $72
- Updated
- 2021/12/16
- Product number
- FB144127
- Product name
- 6-(Bromomethyl)quinoxaline
- Packaging
- 250mg
- Price
- $145
- Updated
- 2021/12/16
- Product number
- FB144127
- Product name
- 6-(Bromomethyl)quinoxaline
- Packaging
- 500mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- FB144127
- Product name
- 6-(Bromomethyl)quinoxaline
- Packaging
- 1g
- Price
- $437
- Updated
- 2021/12/16
- Product number
- HCH0367840
- Product name
- 6-(BROMOMETHYL)QUINOXALINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.69
- Updated
- 2021/12/16
6-(bromomethyl)quinoxaline Chemical Properties,Usage,Production
Synthesis
6344-72-5
53967-21-8
General procedure for the synthesis of 6-bromomethylquinoxaline from 6-methylquinoxaline: a mixture of 6-methylquinoxaline (2.0 g, 13.9 mmol), N-bromosuccinimide (3.0 g, 16.9 mmol), and benzoyl peroxide (411 mg, 1.7 mmol) in anhydrous carbon tetrachloride (50 mL) was subjected to stirring and reacted for 48 hours under reflux conditions . Upon completion of the reaction, the mixture was cooled to room temperature and diluted with the addition of dichloromethane (50 mL). Subsequently, the reaction mixture was washed sequentially with 1N sodium hydroxide solution (1 x 100 mL) and saturated saline (1 x 100 mL). The organic phase was separated, dried with anhydrous magnesium sulfate, filtered and the solvent was concentrated under reduced pressure to give the crude product. Finally, the crude product was purified by fast column chromatography (eluent: 0-30% ethyl acetate/hexane gradient elution) to afford the target compound 6-bromomethylquinoxaline (1.10 g, 35% yield).
References
[1] ChemMedChem, 2017, vol. 12, # 3, p. 257 - 270
[2] Journal of Medicinal Chemistry, 1995, vol. 38, # 4, p. 617 - 628
[3] Patent: WO2010/132999, 2010, A1. Location in patent: Page/Page column 111
[4] Patent: WO2011/23753, 2011, A1. Location in patent: Page/Page column 74-75
6-(bromomethyl)quinoxaline Preparation Products And Raw materials
Raw materials
Preparation Products
6-(bromomethyl)quinoxaline Suppliers
- Tel
- 18049974220
- Fax
- +86 (21) 51062076
- 3060526242@qq.com
- Country
- China
- ProdList
- 998
- Advantage
- 60
- Tel
- 18030648795 18030648795
- Fax
- 028-61777050
- sales@cdforestchem.com
- Country
- China
- ProdList
- 1990
- Advantage
- 58
- Tel
- 021-021-56795766
- Fax
- +86-21-56795266
- sales@worldyachem.com
- Country
- China
- ProdList
- 9478
- Advantage
- 58
- Tel
- 微信 17321281695 18019252918
- Fax
- 17321281695
- sale@amkchem.com
- Country
- China
- ProdList
- 14996
- Advantage
- 55
- Tel
- 021-5068 3667/17749785980/1029026415; 17749785980
- Fax
- 021-50683667
- 1029026415@qq.com
- Country
- China
- ProdList
- 4359
- Advantage
- 58
- Tel
- 021-58892003 18601689453;
- info@qiaochem.com
- Country
- China
- ProdList
- 6060
- Advantage
- 65
- Tel
- 85528066 13775048983
- Fax
- 0519-85528066
- sales@hopschem.com
- Country
- China
- ProdList
- 31553
- Advantage
- 55
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 微信 17321281695 18019252918
- Fax
- 021-31261685
- sale@amkchem.com
- Country
- China
- ProdList
- 9991
- Advantage
- 55
- Tel
- 400-711-5280 86-571-81025280
- Fax
- 86-571-85806285
- sales@molcore.com
- Country
- China
- ProdList
- 9967
- Advantage
- 58