benzo[d]oxazole-6-carboxylic acid
- Product Name
- benzo[d]oxazole-6-carboxylic acid
- CAS No.
- 154235-77-5
- Chemical Name
- benzo[d]oxazole-6-carboxylic acid
- Synonyms
- SB9;Serpin B9-IN-1;6-Benzoxazolecarboxylic acid;Benzoxazole-6-carboxylic Acid;1,3-Benzoxazole-6-carboxylic acid;benzo[d]oxazole-6-carboxylic acid;1,3-Benzoxazole-6-carboxylic acid 97%;1,3-Benzoxazole-6-carboxylic acid, 10 mM in DMSO
- CBNumber
- CB31515852
- Molecular Formula
- C8H5NO3
- Formula Weight
- 163.13
- MOL File
- 154235-77-5.mol
benzo[d]oxazole-6-carboxylic acid Property
- Melting point:
- 280-290 °C (sublm)(Press: 16 Torr)
- Boiling point:
- 350.1±15.0 °C(Predicted)
- Density
- 1.455±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- form
- Solid
- pka
- 3.60±0.30(Predicted)
- color
- Light brown to brown
Safety
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- J98940
- Product name
- Benzo[d]oxazole-6-carboxylicacid
- Packaging
- 1g
- Price
- $40
- Updated
- 2021/12/16
- Product number
- FB44071
- Product name
- Benzo[d]oxazole-6-carboxylic acid
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- OR110125
- Product name
- 1,3-Benzoxazole-6-carboxylicacid
- Purity
- 97%
- Packaging
- 1g
- Price
- $106
- Updated
- 2021/12/16
- Product number
- 4H58-1-368
- Product name
- 1,3-Benzoxazole-6-carboxylic acid
- Packaging
- 1g
- Price
- $117
- Updated
- 2021/12/16
- Product number
- FB44071
- Product name
- Benzo[d]oxazole-6-carboxylic acid
- Packaging
- 2g
- Price
- $120
- Updated
- 2021/12/16
benzo[d]oxazole-6-carboxylic acid Chemical Properties,Usage,Production
Uses
6-?Benzoxazolecarboxyli?c Acid is a reactant used in the design, synthesis, structure-activity relationship, and in vivo activity of azabicyclic aryl amides as α7 nicotinic acetylcholine receptor agonists.
in vivo
Serpin B9-IN-1 (BTCA) inhibits bone metastasis (BM) in multiple tumor metastasis models. Serpin B9-IN-1 (50 mg/kg/d; ip; 14 d) effectively reduced the survival rate and metastasis proportion of metastatic cancer cells in the mouse bone metastasis model with LLC1-BM3 injected into the tail artery (CA)[1].
Serpin B9-IN-1 (300 μg/d; ip; 14 d) effectively delayed the average time to bone metastasis (BM) in the LLC1-BM3 cell group[1].
| Animal Model: | LLC1-BM3 Bone Metastatic Mouse Model by CA injections[1] |
| Dosage: | 50 mg/kg |
| Administration: | ip; followed after cancer cell injection, injection daily for 14 days |
| Result: | Reduced the survival rate and metastasis proportion of metastatic cancer cells |
| Animal Model: | LLC1-BM3-sr-ctrl Model in Mouse[1] |
| Dosage: | 300 μg |
| Administration: | ip; once daily for 14 days |
| Result: | Delayed the mean time to occurrence of bone metastasis (BM), and lowered the burden of BM in LLC1-BM3-shSB9 cells group. |
benzo[d]oxazole-6-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
benzo[d]oxazole-6-carboxylic acid Suppliers
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- Country
- India
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