4-[(2,3-EPOXYPROPOXY)METHYL]-2,2-DIMETHYL-1,3-DIOXOLANE
- Product Name
- 4-[(2,3-EPOXYPROPOXY)METHYL]-2,2-DIMETHYL-1,3-DIOXOLANE
- CAS No.
- 1607-37-0
- Chemical Name
- 4-[(2,3-EPOXYPROPOXY)METHYL]-2,2-DIMETHYL-1,3-DIOXOLANE
- Synonyms
- ISOPROPYLIDENGLYCEROLGLYCIDYL ETHER;4-[(2,3-EPOXYPROPOXY)METHYL]-2,2-DIMETHYL-1,3-DIOXOLANE;2,2-diMethyl-4-[(oxiran-2-ylMethoxy)Methyl]-1,3-dioxolane;1,3-Dioxolane, 2,2-dimethyl-4-[(2-oxiranylmethoxy)methyl]-
- CBNumber
- CB3151754
- Molecular Formula
- C9H16O4
- Formula Weight
- 188.22
- MOL File
- 1607-37-0.mol
4-[(2,3-EPOXYPROPOXY)METHYL]-2,2-DIMETHYL-1,3-DIOXOLANE Property
- Boiling point:
- 136-140 °C(Press: 18 Torr)
- Density
- 1.085±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- Appearance
- Colorless to light yellow Liquid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H227Combustible liquid
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 8112AA
- Product name
- 4-[(2,3-Epoxypropoxy)methyl]-2,2-dimethyl-1,3-dioxolane
- Packaging
- 1g
- Price
- $351
- Updated
- 2021/12/16
- Product number
- LIP0002512
- Product name
- ISOPROPYLIDENGLYCEROLGLYCIDYL ETHER
- Purity
- 98.00%
- Packaging
- 1G
- Price
- $1189.65
- Updated
- 2021/12/16
- Product number
- LIP0002512
- Product name
- ISOPROPYLIDENGLYCEROLGLYCIDYL ETHER
- Purity
- 98.00%
- Packaging
- 5G
- Price
- $3130.05
- Updated
- 2021/12/16
- Product number
- CD11244672
- Product name
- 4-[(2,3-Epoxypropoxy)methyl]-2,2-dimethyl-1,3-dioxolane
- Purity
- 95+%
- Packaging
- 1g
- Price
- $221
- Updated
- 2021/12/16
- Product number
- 1607370
- Product name
- 4-[(2,3-Epoxypropoxy)methyl]-2,2-dimethyl-1,3-dioxolane
- Packaging
- 1g
- Price
- $226.84
- Updated
- 2021/12/16
4-[(2,3-EPOXYPROPOXY)METHYL]-2,2-DIMETHYL-1,3-DIOXOLANE Chemical Properties,Usage,Production
Synthesis
106-89-8
100-79-8
1607-37-0
1-Chloro-2,3-epoxypropane (198 mmol) was mixed with 2,2-dimethyl-1,3-dioxolane-4-methanol (98 mmol) in benzene (20 mL) and 50% aqueous NaOH (20 mL), and tetra-n-butylammonium bromide (TBAB, 10 mmol) was added as a phase transfer catalyst. The reaction mixture was stirred at 0 °C for 48 hours. After completion of the reaction, the reaction mixture was diluted with ether and washed sequentially with water (3 × 75 mL), saturated NaHCO3 solution (3 × 75 mL) and brine (3 × 75 mL). The organic phase was dried with anhydrous Na2SO4, filtered and concentrated under reduced pressure. The crude product was purified by reduced pressure distillation (165 °C, 1.2 mbar, boiling point 90 °C) to give 4-[(2,3-epoxypropoxy)methyl]-2,2-dimethyl-1,3-dioxolane (3b) as a colorless liquid in 29% yield.1H NMR (500 MHz, CDCl3): δ 1.34 (s, 3H, CH3), 1.40 (s, 3H, CH3), 2.58 (ddd, J = 5.0, 3.9, 2.7 Hz, 1H, H-7), 2.73-2.82 (m, 1H, H-7), 3.08-3.18 (m, 1H), 3.40 (ddd, J = 17.6, 11.7, 6.0 Hz, 1H), 3.46-3.64 (m, 2H), 3.71 (td, J = 8.3, 6.4 Hz, 1H), 3.80 (ddd, J = 13.4, 11.7, 2.9 Hz, 1H), 4.04 (ddd, J = 8.0, 6.4, 1.5 Hz, 1H), 4.27 (dq, J = 11.6, 5.8, 5.3 Hz, 1H, H-1) ppm.1H NMR data are in agreement with the literature reports.
References
[1] Macromolecules, 2010, vol. 43, # 13, p. 5582 - 5588
[2] Inorganica Chimica Acta, 2016, vol. 452, p. 159 - 169
[3] Tetrahedron, 1996, vol. 52, # 18, p. 6437 - 6452
[4] Patent: US4927941, 1990, A
[5] Patent: US4977273, 1990, A
4-[(2,3-EPOXYPROPOXY)METHYL]-2,2-DIMETHYL-1,3-DIOXOLANE Preparation Products And Raw materials
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