4-Bromo-2-cyanobenzaldehyde
- Product Name
- 4-Bromo-2-cyanobenzaldehyde
- CAS No.
- 523977-64-2
- Chemical Name
- 4-Bromo-2-cyanobenzaldehyde
- Synonyms
- 4-Bromo-2-cyanobenzaldehyde;5-Bromo-2-formylbenzonitrile;2-Cyano-4-bromo-benzaldehyde;Benzonitrile, 5-bromo-2-formyl-
- CBNumber
- CB31563671
- Molecular Formula
- C8H4BrNO
- Formula Weight
- 210.03
- MOL File
- 523977-64-2.mol
4-Bromo-2-cyanobenzaldehyde Property
- Boiling point:
- 324℃
- Density
- 1.65
- Flash point:
- 150℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- solid
- Appearance
- Off-white to light brown Solid
N-Bromosuccinimide Price
- Product number
- B614275
- Product name
- 4-Bromo-2-cyanobenzaldehyde
- Packaging
- 500mg
- Price
- $285
- Updated
- 2021/12/16
- Product number
- B614275
- Product name
- 4-Bromo-2-cyanobenzaldehyde
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 096450
- Product name
- 4-Bromo-2-cyanobenzaldehyde
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $265
- Updated
- 2021/12/16
- Product number
- HCH0104618
- Product name
- 4-BROMO-2-CYANOBENZALDEHYDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.02
- Updated
- 2021/12/16
- Product number
- 7389AB
- Product name
- 4-Bromo-2-cyanobenzaldehyde
- Packaging
- 1g
- Price
- $523
- Updated
- 2021/12/16
4-Bromo-2-cyanobenzaldehyde Chemical Properties,Usage,Production
Application
4-Bromo-2-cyanobenzaldehyde is a useful research chemical.
Synthesis
156001-53-5
523977-64-2
General procedure for the synthesis of 4-bromo-2-cyanobenzaldehyde from 5-bromo-2-(bromomethyl)benzonitrile: To a stirred solution of trimethylamine N-oxide dihydrate (16.98 g, 152.8 mmol) in DMSO (60 mL) was added 5-bromo-2-(bromomethyl)benzonitrile (from step 1, 10.5 g, 38.19 mmol) in DCM (30 mL) to the solution in DCM. The resulting mixture was added slowly at 5 °C, followed by warming to 22 °C and continued stirring for 6 hours. After completion of the reaction, the reaction mixture was diluted with DCM (70 mL), washed sequentially with brine (20 mL × 3), dried over anhydrous Na2SO4, filtered and concentrated in vacuum. The residue was purified by silica gel column chromatography (eluent: 0-16% EtOAc in petroleum ether solution) to afford 4-bromo-2-cyanobenzaldehyde (4.2 g, 52% yield) as a white solid.1H NMR (400 MHz, CDCl3) δ 10.31 (s, 1H), 7.98 (s, 1H), 7.92 (s, 2H).
References
[1] Organic Letters, 2003, vol. 5, # 7, p. 1131 - 1134
[2] Journal of Materials Chemistry, 2011, vol. 21, # 26, p. 9523 - 9531
[3] Patent: US2017/362228, 2017, A1. Location in patent: Paragraph 0466; 0467
4-Bromo-2-cyanobenzaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
4-Bromo-2-cyanobenzaldehyde Suppliers
- Tel
- --
- Fax
- --
- contact@achemica.com
- Country
- Switzerland
- ProdList
- 6155
- Advantage
- 50
View Lastest Price from 4-Bromo-2-cyanobenzaldehyde manufacturers
- Product
- 4-Bromo-2-cyanobenzaldehyde 523977-64-2
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-09
- Product
- 4-Bromo-2-cyanobenzaldehyde 523977-64-2
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-09