Nilutamide-d6
- Product Name
- Nilutamide-d6
- CAS No.
- 1189477-66-4
- Chemical Name
- Nilutamide-d6
- Synonyms
- RU 23908-d6;Anandron-d6;Nilandron-d6;Nilutamide-d6;Nilandrone-d6;Niludipine D6;D6-Nilutamide;RU 23908-10-d6;[2H6]-Nilutamide;1-(3-Trifluoromethyl-4-nitrophenyl)-4,4-(dimethyl-d6)imidazoline-2,5-dione
- CBNumber
- CB31564906
- Molecular Formula
- C12H10F3N3O4
- Formula Weight
- 317.2207096
- MOL File
- 1189477-66-4.mol
Nilutamide-d6 Property
- Melting point:
- 1490C
- storage temp.
- Store at -20°C
- solubility
- DMSO: soluble
- form
- A solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 28694
- Product name
- Nilutamide-d6
- Purity
- ≥99%deuteratedforms(d<sub>1</sub>-d<sub>6</sub>)
- Packaging
- 1mg
- Price
- $369
- Updated
- 2026/04/30
- Product number
- 28694
- Product name
- Nilutamide-d6
- Packaging
- 1mg
- Price
- $335
- Updated
- 2024/03/01
- Product number
- N467502
- Product name
- Nilutamide-d6
- Packaging
- 1mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- 018141
- Product name
- Nilutamide-d6
- Packaging
- 1mg
- Price
- $446
- Updated
- 2021/12/16
- Product number
- 7811DG
- Product name
- Nilutamide-d6
- Packaging
- 1mg
- Price
- $471
- Updated
- 2021/12/16
Nilutamide-d6 Chemical Properties,Usage,Production
Description
Nilutamide-d6 is intended for use as an internal standard for the quantification of nilutamide by GC- or LC-MS. Nilutamide is a non-steroidal antiandrogen that is an antagonist of the androgen receptor. It reverses testosterone-induced increases in cell proliferation with an IC50 value of 412 nM in mouse mammary carcinoma cells in vitro. It has antiandrogenic activity in both intact and castrated rats, inhibiting testosterone propionate-induced prostate growth when administered at a dose of 2.5 mg/kg. Formulations containing nilutamide have been used in combination with surgical castration in the treatment of metastatic prostate cancer.
Chemical Properties
Nilutamide-d6 is Crystalline Solid
Uses
Nilutamide-d6 intended for use as an internal standard for the quantification of Nilutamide by GC- or LC-mass spectrometry.
Uses
Nonsteroidal antiandrogen. Antineoplastic (hormonal)
References
[1] S M SINGH F L S Gauthier. Androgen receptor antagonists (antiandrogens): structure-activity relationships.[J]. Current medicinal chemistry, 2000, 7 2: 211-247. DOI: 10.2174/0929867003375371
[2] JACQUES SIMARD Fernand L Shankar Mohan Singh. Comparison of in vitro effects of the pure antiandrogens OH-flutamide, casodex, and nilutamide on androgen-sensitive parameters[J]. Urology, 1997, 49 4: Pages 580-589. DOI: 10.1016/s0090-4295(97)00029-0
[3] A.E. WAKELING. Receptor binding and biological activity of steroidal and nonsteroidal antiandrogens[J]. Journal of steroid biochemistry, 1981, 15: Pages 355-359. DOI: 10.1016/0022-4731(81)90297-1
Nilutamide-d6 Preparation Products And Raw materials
Raw materials
Preparation Products
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