Butyrophenone

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Description References

Product Name: Butyrophenone
CAS No.: 495-40-9
Chemical Name: Butyrophenone
Synonyms: 1-Phenylbutan-1-one;Butanophenone;1-PHENYL-1-BUTANONE;Propyl phenyl ketone;BUTYROPHENONE;Buterophenone;Buthrophenone;Butyrylbenzene;N-BUTYROPHENONE;N-BUTANOPHENONE
CBNumber: CB3167698
Molecular Formula: C10H12O
Formula Weight: 148.2
MOL File: 495-40-9.mol

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Butyrophenone Property

Melting point:: 11-13 °C(lit.)
Boiling point:: 228-230 °C(lit.)
Density: 1.021 g/mL at 25 °C(lit.)
refractive index: n20/D 1.520(lit.)
Flash point:: 192 °F
storage temp.: Store below +30°C.
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Liquid
Specific Gravity: 0.988
color: Clear colorless to yellow
Odor: at 100.00 %. camphor cherry walnut hazelnut
Odor Type: camphoreous
Water Solubility: Insoluble in water.
BRN: 508305
Stability:: Stable. Combustible. Incompatible with strong oxidizing agents.
LogP: 2.770
CAS DataBase Reference: 495-40-9(CAS DataBase Reference)
NIST Chemistry Reference: 1-Butanone, 1-phenyl-(495-40-9)
EPA Substance Registry System: 1-Butanone, 1-phenyl- (495-40-9)

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Safety

Hazard Codes: Xi
Risk Statements: 41-43
Safety Statements: 26-36/37/39-24/25-23
WGK Germany: 3
TSCA: Yes
HS Code: 29143900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H227Combustible liquid

H317May cause an allergic skin reaction

H318Causes serious eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 124338
Product name: Butyrophenone
Purity: ≥99%
Packaging: 25g
Price: $59
Updated: 2024/03/01

Sigma-Aldrich

Product number: 124338
Product name: Butyrophenone
Purity: ≥99%
Packaging: 100g
Price: $217
Updated: 2024/03/01

TCI Chemical

Product number: B0769
Product name: Butyrophenone
Purity: >99.0%(GC)
Packaging: 25mL
Price: $28
Updated: 2024/03/01

TCI Chemical

Product number: B0769
Product name: Butyrophenone
Purity: >99.0%(GC)
Packaging: 100mL
Price: $87
Updated: 2024/03/01

Alfa Aesar

Product number: A11345
Product name: Butyrophenone, 99%
Packaging: 25g
Price: $28.65
Updated: 2024/03/01

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Butyrophenone Chemical Properties,Usage,Production

Description

Butyrophenone is a chemical compound with the formula C10H12O. Butyrophenone has been used to study the relationship between the electrolyte counter-ion concentration and the critical micelle concentration for several surfactants. It has been used to generate PhCO+ ions by 70 eV electron ionization. Some of its derivatives (called commonly butyrophenones) are used to treat various psychiatric disorders such as schizophrenia, as well as acting as antiemetics. They can interfere with neurotransmitter functions, usually blocking dopamine receptors, and induce behavioral, endocrine, motor-kinetic effects. Examples of butyrophenones include: Haloperidol, the most widely used classical antipsychotic drug in this class; Benperidol, the most potent commonly used antipsychotic ( 200 times more potent than chlorpromazine).

References

1. https://en.wikipedia.org/wiki/Butyrophenone
2. http://www.rightdiagnosis.com/medical/butyrophenone.htm
3. http://www.sigmaaldrich.com/catalog/product/aldrich/124338?lang=en&region=CA

Chemical Properties

colourless to yellow liquid

Uses

Butyrophenone is used as intermediates of Liquid Crystals

Uses

Intermediates of Liquid Crystals

Synthesis Reference(s)

The Journal of Organic Chemistry, 61, p. 376, 1996 DOI: 10.1021/JO951500R
Tetrahedron Letters, 30, p. 6357, 1989 DOI: 10.1016/S0040-4039(01)93893-6

Biochem/physiol Actions

Butyrophenones constitutes neuroleptic drugs and interacts with the opiate receptor by inhibiting the stereospecific binding of 3H-naloxone.

Butyrophenone Preparation Products And Raw materials

Raw materials

Butyryl chloride

Preparation Products

Haloperidol Ethacrynic acid

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View Lastest Price from Butyrophenone manufacturers

Hebei Guanlang Biotechnology Co., Ltd.

Product: Butyrophenone 495-40-9
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99.5%
Supply Ability: 100
Release date: 2020-11-19

Zhuozhou Wenxi import and Export Co., Ltd

Product: Butyrophenone, Phenyl n-propyl ketone 495-40-9
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: Butyrophenone 495-40-9
Price: US $1.80-3.60/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 88kg
Release date: 2019-07-30

495-40-9, ButyrophenoneRelated Search:

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1-PHENYL-1-BUTANONE

1-Butanone,1-phenyl-

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1-phenyl-butan-1-one

1-Phenylbutan-1-one

Butyrylbenzene

Propyl phenyl ketone

N-BUTANOPHENONE

N-BUTYROPHENONE

N-PROPYL PHENYL KETONE

PHENYL PROPYL KETONE

PHENYL N-PROPYL KETONE

BUTYROPHENONE, 99+%

N-BUTYROPHENONE 99%

n-butyrophenone, phenyl-n-propyl ketone

BUTYROPHENONE

Butanophenone

n-Butyrophenone,99%

1-Phenylbutan-1-one, Phenyl propyl ketone

n-Butyrophenone, 99% 100ML

Buterophenone

Butyrophenone, Phenyl n-propyl ketone

Naproxen Impurity 9

Butyrophenone &gt

BUTYROPHENONE FOR SYNTHESIS 250 ML

BUTYROPHENONE FOR SYNTHESIS 25 ML

Naproxen Impurity 37

Butyrophenone, puriss, 99%+

Butyrophenone, puriss

Butyrophenone (6CI, 8CI)

BORON TRIBROMIDE 1M in N-Heptane

Butyrophenone, 99% (Custom work)

Buthrophenone

Butyrophenone, ≥ 99.0%

495-40-9

C6H5COCH2CH2CH3

C2H5CH2COC6H5

C3H7COC6H5

CH3CH2CH2COC6H5

Organic Building Blocks

Ketones

Building Blocks

Carbonyl Compounds

C10

KETONE

Building Blocks

C10

Carbonyl Compounds

Chemical Synthesis

Ketones

Organic Building Blocks

Pharmaceutical Intermediates

Aromatic Ketones (substituted)

ketone