Description Structure ?Discovery Biological functions
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CCAP

Description Structure ?Discovery Biological functions
Product Name
CCAP
CAS No.
107090-96-0
Chemical Name
CCAP
Synonyms
CCAP;CCAP, AMIDE;CRUSTACEAN CARDIOACTIVE PEPTIDE;PRO-PHE-CYS-ASN-ALA-PHE-THR-GLY-CYS;CRUSTACEAN CARDIOACTIVE PEPTIDE, AMIDE;PRO-PHE-CYS-ASN-ALA-PHE-THR-GLY-CYS-NH2;H-PRO-PHE-CYS-ASN-ALA-PHE-THR-GLY-CYS-NH2;Crustacean Cardioactive Peptide (CCAP), amide;Crustacean Cardioactive Peptide H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-NH2 (Disulfide bond);L-Cysteinamide, L-prolyl-L-phenylalanyl-L-cysteinyl-L-asparaginyl-L-alanyl-L-phenylalanyl-L-threonylglycyl-, cyclic (3→9)-disulfide
CBNumber
CB3174599
Molecular Formula
C42H57N11O11S2
Formula Weight
956.1
MOL File
107090-96-0.mol
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CCAP Property

storage temp. 
-15°C
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Alfa Aesar
Product number
J66453
Product name
Crustacean Cardioactive Peptide
Packaging
10mg
Price
$527
Updated
2023/06/20
Alfa Aesar
Product number
J66453
Product name
Crustacean Cardioactive Peptide
Packaging
5mg
Price
$213
Updated
2021/12/16
Usbiological
Product number
C7937
Product name
Crustacean Cardioactive Peptide
Packaging
1mg
Price
$531
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC109960
Product name
Crustacean Cardioactive Peptide H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-NH2 (Disulfide bond)
Packaging
1mg
Price
$131
Updated
2021/12/16
Biorbyt Ltd
Product number
orb364486
Product name
CCAP amide
Purity
> 95%
Packaging
5mg
Price
$552.5
Updated
2021/12/16
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CCAP Chemical Properties,Usage,Production

Description

CCAP, the most conserved neuropeptide found in arthropods, has been identified in various insects and crustaceans as a factor in cardioacceleratory action. It is also expressed in a conserved network of segmental neurons that controls ecdysis.

Structure

CCAP is a cyclic amidated nonapeptide, including two Cys residues that form a disulfide bond. Amidation is crucial for biological activity.

?Discovery

The crustacean cardioactive peptide (CCAP) was originally identified from the central nervous system (CNS) of the crab Carcinus maenas, based on its heart stimulatory activity.An identical neuropeptide and the gene encoding a single copy of CCAP were later identified or annotated in many other insects and crustaceans.

Biological functions

CCAP acts on the heart to elicit increased frequency and amplitude of the heartbeat in crustaceans and insects.Its main central role is to induce the specific ecdysis behavior in moths.In R. prolixus, CCAP proved to be essential for successful ecdysis and development.Also, physiological and genetic experiments indicate that CCAP acts together with myoinhibitory peptides and the bursicon subunit (pburs) to control ecdysis behavior.In feeding cockroaches, CCAP is released from midgut endocrine cells to stimulate α-amylase and protease activity in the intestine.

CCAP Preparation Products And Raw materials

Raw materials

Preparation Products

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CCAP Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
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View Lastest Price from CCAP manufacturers

Career Henan Chemical Co
Product
CCAP 107090-96-0
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
200g
Release date
2020-02-01

107090-96-0, CCAPRelated Search:


  • CRUSTACEAN CARDIOACTIVE PEPTIDE
  • CRUSTACEAN CARDIOACTIVE PEPTIDE, AMIDE
  • CCAP
  • CCAP, AMIDE
  • H-PRO-PHE-CYS-ASN-ALA-PHE-THR-GLY-CYS-NH2
  • PRO-PHE-CYS-ASN-ALA-PHE-THR-GLY-CYS
  • PRO-PHE-CYS-ASN-ALA-PHE-THR-GLY-CYS-NH2
  • Crustacean Cardioactive Peptide (CCAP), amide
  • Crustacean Cardioactive Peptide H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-NH2 (Disulfide bond)
  • L-Cysteinamide, L-prolyl-L-phenylalanyl-L-cysteinyl-L-asparaginyl-L-alanyl-L-phenylalanyl-L-threonylglycyl-, cyclic (3→9)-disulfide
  • 107090-96-0
  • C42H57N11O11S2