ChemicalBook > CAS DataBase List > PD 117519

PD 117519

Product Name
PD 117519
CAS No.
96392-15-3
Chemical Name
PD 117519
Synonyms
CI 947;PD 11751;PD 117519;PD 117519,R;PD 117519 (CI947);PD 117519, 10 mM in DMSO;N-[(R)-Indan-1-yl]adenosine;N-[(1R)-Indan-1-yl]adenosine;(R)-N-(2,3-Dihydro-1H-indenyl)adenosine;PD-117519;PD 117519;PD117519;CI 947;CI947
CBNumber
CB31872452
Molecular Formula
C19H21N5O4
Formula Weight
383.4
MOL File
96392-15-3.mol
More
Less

PD 117519 Property

storage temp. 
2-8°C
solubility 
DMF: 10mg/mL; DMF:PBS (pH 7.2) (1:4): 0.2mg/mL; DMSO: 5mg/mL; Ethanol: 0.1mg/mL
form 
A solid
color 
White to off-white
InChIKey
FSKMJUWPFLDDRS-BYMDKACISA-N
SMILES
OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N[C@H]3C4=C(C=CC=C4)CC3)N=C2)[C@H](O)[C@@H]1O
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
28444
Product name
PD 117519
Packaging
5mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
28444
Product name
PD 117519
Packaging
10mg
Price
$100
Updated
2024/03/01
Cayman Chemical
Product number
28444
Product name
PD 117519
Packaging
25mg
Price
$208
Updated
2024/03/01
Cayman Chemical
Product number
28444
Product name
PD 117519
Packaging
50mg
Price
$384
Updated
2024/03/01
TRC
Product number
D449160
Product name
(R)-N-(2,3-Dihydro-1H-indenyl)adenosine
Packaging
50mg
Price
$340
Updated
2021/12/16
More
Less

PD 117519 Chemical Properties,Usage,Production

Uses

N6-Substituted adenosine receptor agonist; a potential antihypertensive agent.

in vitro

PD 117519 (2-10 mg/kg; oral administration; 16-24 hours; male beagle dogs) treatment produces significant hemodynamic changes at Tmax (4 hours) follows by acute coronary vascular injury that is evident at 16 hours postdosing.Treatment with 2 or 10 mg/kg of PD 117519 produces significant increases in mean heart rate and decreases in mean indirectsystolic blood pressure at time of highest drug exposure, 4 hours postdosing.

in vivo

PD 117519 (2-10 mg/kg; oral administration; 16-24 hours; male beagle dogs) treatment produces significant hemodynamic changes at Tmax (4 hours) follows by acute coronary vascular injury that is evident at 16 hours postdosing.Treatment with 2 or 10 mg/kg of PD 117519 produces significant increases in mean heart rate and decreases in mean indirectsystolic blood pressure at time of highest drug exposure, 4 hours postdosing[3].

Animal Model:24 male beagle dogs (8-12 months old)[3]
Dosage:2 mg/kg or 10 mg/kg
Administration:Oral administration; 16 hours and 24 hours
Result:Increased in mean heart rate and decreased in mean indirectsystolic blood pressure at time of highest drug exposure. Induced acute coronary arteriopathy. The endothelium also appears injured.

PD 117519 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

PD 117519 Suppliers

Canada 1 China 64 India 1 Switzerland 1 United Kingdom 3 United States 8 Global 78
Zhengzhou Granlen Sciences, ltd.
Tel
0371-85513397 +86-18610099868
Email
info@granlen.com
Country
China
ProdList
1890
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Fax
Pls mail us for more information!
Email
info@sagechem.com
Country
China
ProdList
10266
Advantage
58
Nanjing Baifuli Technology Co., Ltd.
Tel
25-25-58740604 15951658055
Fax
+86-25-58356858
Email
sales@unisyn.cn
Country
China
ProdList
591
Advantage
58
Zhengzhou GranLen pharmaceutical Technology Co., Ltd.
Tel
0371-85513397
Email
info@granlen.com
Country
China
ProdList
497
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66028182 18626450290
Email
yftan@aikonchem.com
Country
China
ProdList
16679
Advantage
50
Shanghai Beckham Medical Technology Co., Ltd
Tel
13816613772
Fax
QQ: 12922499
Email
huahero21@sina.com
Country
China
ProdList
2391
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60

96392-15-3, PD 117519Related Search:


  • (R)-N-(2,3-Dihydro-1H-indenyl)adenosine
  • N-[(1R)-Indan-1-yl]adenosine
  • N-[[(R)-2,3-Dihydro-1H-inden]-1α-yl]adenosine
  • CI 947
  • N-[(1R)-2,3-Dihydro-1H-inden-1-yl]adenosine
  • PD 117519
  • N-[(R)-Indan-1-yl]adenosine
  • Adenosine, N-[(1R)-2,3-dihydro-1H-inden-1-yl]-
  • PD 117519,R
  • PD 11751
  • PD-117519;PD 117519;PD117519;CI 947;CI947
  • N-[(R)-Indan-1-yl] adenosine, Drug, N-substituted adenosine receptor agonist, a potential antihypertensive agent
  • N-[(R)-Indan-1-yl]adenosine, PD-117519, CI947
  • CI-947,PD-117519,Adenosine Receptor,Inhibitor,P1 receptor,PD117519,PD 117519,inhibit,CI 947
  • PD 117519 (CI947)
  • (2R,3R,4S,5R)-2-(6-(((R)-2,3-Dihydro-1H-inden-1-yl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
  • PD 117519, 10 mM in DMSO
  • 96392-15-3
  • Bases & Related Reagents
  • Carbohydrates & Derivatives
  • Intermediates & Fine Chemicals
  • Nucleotides
  • Pharmaceuticals