Succinylsulfathiazole
Description Background- Product Name
- Succinylsulfathiazole
- CAS No.
- 116-43-8
- Chemical Name
- Succinylsulfathiazole
- Synonyms
- SST;SMST;rolsul;THIACYL;kaoxidin;KAOXIDINE;colistatin;sulfadigesin;SULFENTERONE;SST-PB3M-CPX
- CBNumber
- CB3187922
- Molecular Formula
- C13H13N3O5S2
- Formula Weight
- 355.39
- MOL File
- 116-43-8.mol
Succinylsulfathiazole Property
- Melting point:
- 193.5°C
- Density
- 1.4807 (rough estimate)
- refractive index
- 1.6390 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- 1 M NaOH: soluble50mg/mL
- pka
- pKa 4.5 (Uncertain)
- form
- powder
- color
- white to off-white
- Water Solubility
- 0.49g/L(38 ºC)
- λmax
- 282nm(H2O (pH 3.3 - 5))(lit.)
- Merck
- 14,8877
- BRN
- 349989
- CAS DataBase Reference
- 116-43-8(CAS DataBase Reference)
- EPA Substance Registry System
- Butanoic acid, 4-oxo-4-[[4-[(2-thiazolylamino)sulfonyl]phenyl]amino]- (116-43-8)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 42/43
- Safety Statements
- 22-36/37-45
- RIDADR
- 3249
- WGK Germany
- 3
- RTECS
- WM4767000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29350090
N-Bromosuccinimide Price
- Product number
- S364843
- Product name
- N1-(2-THIAZOLYL)-N4-SUCCINOYLSULFANILAMIDE
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $113
- Updated
- 2025/07/31
- Product number
- S364843
- Product name
- N1-(2-THIAZOLYL)-N4-SUCCINOYLSULFANILAMIDE
- Purity
- Aldrich
- Packaging
- 250mg
- Price
- $110
- Updated
- 2024/03/01
- Product number
- S0991
- Product name
- Succinylsulfathiazole
- Purity
- >97.0%(HPLC)
- Packaging
- 25g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- 359043
- Product name
- Sst
- Packaging
- 48Tests
- Price
- $588
- Updated
- 2021/12/16
- Product number
- 384508
- Product name
- SST
- Packaging
- 96Tests
- Price
- $729
- Updated
- 2021/12/16
Succinylsulfathiazole Chemical Properties,Usage,Production
Originator
Sulfasuxidine,MSD,US,1942
Uses
Succinylsulfathiazole is a sulfonamide antibiotic that was shown to inhibit bacteria that are responsible for folate production. Succinylsulfathiazole was used in various folate deficiency studies to block the synthesis of folic acid.
Uses
Succinylsulfathiazole is antibacterial
Definition
ChEBI: N-succinylsulfathiazole is a member of 1,3-thiazoles. It is functionally related to a sulfathiazole.
Manufacturing Process
3.92 g of succinic anhydride was added to a boiling suspension of 10 g of 2- sulfanilamidothiazole in 100 cc of alcohol. The mixture was then refluxed for five minutes after the addition was complete at which time all of the solids were in solution. The solution was then cooled and diluted with an equal volume of water. The white solid precipitate which formed was filtered and recrystallized from dilute alcohol, yielding 2-N4-succinylsulfanilamidothiazole, melting at 184°C to 186°C.
Therapeutic Function
Antibacterial (intestinal)
Description
Somatostatin Synthetic is a single, non-glycosylated polypeptide chain containing 14 amino acids, having a molecular mass of 1637.9 Dalton and a Molecular formula of C76H104N18O19S2. The CAS# is 38916-34-6.
Background
Somatostatin (also known as growth hormone inhibiting hormone (GHIH) or somatotropin release-inhibiting hormone (SRIF) is a peptide hormone that regulates the endocrine systemand affects neurotransmission and cell proliferation via interaction with G-protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones. Somatostatin has two active forms produced by alternative cleavage of a single preproprotein: one of 14 amino acids, the other of 28 amino acids.
References
[1] Pharmaceutical Chemistry Journal, 1997, vol. 31, # 9, p. 471 - 473
[2] Patent: US2007/292352, 2007, A1. Location in patent: Page/Page column 45
[3] Patent: US2324013, 1941,
[4] Journal of the American Chemical Society, 1942, vol. 64, p. 1572,1573, 1574
[5] Patent: US2324014, 1941,
Succinylsulfathiazole Preparation Products And Raw materials
Raw materials
Preparation Products
Succinylsulfathiazole Suppliers
- Tel
- 022-83946278 13820503911
- Fax
- 022-83945176
- sales@creasyn.com
- Country
- China
- ProdList
- 957
- Advantage
- 68
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15838
- Advantage
- 69
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14101
- Advantage
- 59
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 4009903999 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18729
- Advantage
- 57
- Tel
- Fax
- E-Mail Inquiry
- info@syntechem.com
- Country
- China
- ProdList
- 12984
- Advantage
- 57
View Lastest Price from Succinylsulfathiazole manufacturers
- Product
- Succinylsulfathiazole 116-43-8
- Price
- US $65.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000kg/week
- Release date
- 2024-05-27
- Product
- Succinylsulfathiazole 116-43-8
- Price
- US $0.00/kg
- Min. Order
- 20kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2024-10-15
- Product
- Succinylsulfathiazole (SST) 116-43-8
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1Kg
- Purity
- 99.9%
- Supply Ability
- 200tons
- Release date
- 2024-04-08