ChemicalBook > CAS DataBase List > 3-bromo-N'-[1-(2,4-dihydroxyphenyl)ethylidene]-4-methylbenzohydrazide

3-bromo-N'-[1-(2,4-dihydroxyphenyl)ethylidene]-4-methylbenzohydrazide

Product Name
3-bromo-N'-[1-(2,4-dihydroxyphenyl)ethylidene]-4-methylbenzohydrazide
CAS No.
468747-17-3
Chemical Name
3-bromo-N'-[1-(2,4-dihydroxyphenyl)ethylidene]-4-methylbenzohydrazide
Synonyms
mTOR inhibitor-1;mTOR inhibitor-1, 10 mM in DMSO;3-bromo-N'-[1-(2,4-dihydroxyphenyl)ethylidene]-4-methylbenzohydrazide;(E)-3-Bromo-N'-[1-(2,4-dihydroxyphenyl)ethylidene]-4-methylbenzohydrazide;3-Bromo-4-methylbenzoic Acid 2-[1-(2,4-Dihydroxyphenyl)ethylidene]hydrazide;Benzoic acid, 3-bromo-4-methyl-, 2-[1-(2,4-dihydroxyphenyl)ethylidene]hydrazide;mTOR inhibitor1,Mammalian target of Rapamycin,mTOR,inhibit,mTOR inhibitor 1,mTOR inhibitor-1,Inhibitor,Autophagy
CBNumber
CB31910868
Molecular Formula
C16H15BrN2O3
Formula Weight
363.21
MOL File
468747-17-3.mol
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3-bromo-N'-[1-(2,4-dihydroxyphenyl)ethylidene]-4-methylbenzohydrazide Property

Density 
1.48±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : 83.33 mg/mL (229.43 mM; Need ultrasonic)
form 
Solid
pka
7.96±0.40(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
T3934
Product name
mTOR Inhibitor-1
Packaging
5MG
Price
$105
Updated
2026/03/19
TCI Chemical
Product number
T3934
Product name
mTOR Inhibitor-1
Packaging
25MG
Price
$314
Updated
2026/03/19
ChemScene
Product number
CS-0067951
Product name
mTORinhibitor-1
Purity
99.29%
Packaging
5mg
Price
$250
Updated
2021/12/16
ChemScene
Product number
CS-0067951
Product name
mTORinhibitor-1
Purity
99.29%
Packaging
10mg
Price
$450
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573412
Product name
mTOR inhibitor-1
Purity
>98%
Packaging
100mg
Price
$912.9
Updated
2021/12/16
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3-bromo-N'-[1-(2,4-dihydroxyphenyl)ethylidene]-4-methylbenzohydrazide Chemical Properties,Usage,Production

Uses

mTOR inhibitor-1 (Compound C-4) is an ATP-Competitive mTOR inhibitor which can suppress cells proliferation and inducing autophagy[1].

References

[1] Liu J, et al. In Silico Discovery of a Small Molecule Suppressing Lung Carcinoma A549 Cells Proliferation and Inducing Autophagy via mTOR Pathway Inhibition. Mol Pharm. 2018 Nov 5;15(11):5427-5436. DOI:10.1021/acs.molpharmaceut.8b00996

3-bromo-N'-[1-(2,4-dihydroxyphenyl)ethylidene]-4-methylbenzohydrazide Preparation Products And Raw materials

Raw materials

Preparation Products

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3-bromo-N'-[1-(2,4-dihydroxyphenyl)ethylidene]-4-methylbenzohydrazide Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
40000
Advantage
60
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7777
Advantage
56
Shanghaizehan biopharma technology co., Ltd.
Tel
021-61350663 13052117465
Fax
021-61350662
Email
sales@zehanbiopharma.com
Country
China
ProdList
979
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
86249
Advantage
60
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
9675
Advantage
55
Shanghai Rechem science Co., Ltd.
Tel
021-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2990
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9505
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Heze Development Zone chuangli Chemical Co., Ltd.
Tel
0530-+86-530-529 6766,+86-15666160102 15666160102
Fax
0530-529 6766
Email
info@chuangli-chem.com
Country
China
ProdList
840
Advantage
55

468747-17-3, 3-bromo-N'-[1-(2,4-dihydroxyphenyl)ethylidene]-4-methylbenzohydrazideRelated Search:


  • 3-bromo-N'-[1-(2,4-dihydroxyphenyl)ethylidene]-4-methylbenzohydrazide
  • mTOR inhibitor-1
  • Benzoic acid, 3-bromo-4-methyl-, 2-[1-(2,4-dihydroxyphenyl)ethylidene]hydrazide
  • (E)-3-Bromo-N'-[1-(2,4-dihydroxyphenyl)ethylidene]-4-methylbenzohydrazide
  • 3-Bromo-4-methylbenzoic Acid 2-[1-(2,4-Dihydroxyphenyl)ethylidene]hydrazide
  • mTOR inhibitor1,Mammalian target of Rapamycin,mTOR,inhibit,mTOR inhibitor 1,mTOR inhibitor-1,Inhibitor,Autophagy
  • mTOR inhibitor-1, 10 mM in DMSO
  • 468747-17-3