6-DIMETHYLAMINO-2-NAPHTHALDEHYDE
- Product Name
- 6-DIMETHYLAMINO-2-NAPHTHALDEHYDE
- CAS No.
- 173471-71-1
- Chemical Name
- 6-DIMETHYLAMINO-2-NAPHTHALDEHYDE
- Synonyms
- 6-DIMETHYLAMINO-2-NAPHTHALDEHYDE;6-(dimethylamino)naphthalene-2-carbaldehyde;6-(Dimethylamino)-2-naphthalenecarboxaldehyde;2-Naphthalenecarboxaldehyde, 6-(dimethylamino)-
- CBNumber
- CB3191408
- Molecular Formula
- C13H13NO
- Formula Weight
- 199.25
- MOL File
- 173471-71-1.mol
6-DIMETHYLAMINO-2-NAPHTHALDEHYDE Property
- Boiling point:
- 370.4±17.0 °C(Predicted)
- Density
- 1.150±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 3.55±0.40(Predicted)
- Appearance
- Light yellow to yellow Solid
- InChI
- InChI=1S/C13H13NO/c1-14(2)13-6-5-11-7-10(9-15)3-4-12(11)8-13/h3-9H,1-2H3
- InChIKey
- IVFSOOIWIYPDLX-UHFFFAOYSA-N
- SMILES
- C1=C2C(C=C(N(C)C)C=C2)=CC=C1C=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D462363
- Product name
- 6-(Dimethylamino)-2-naphthaldehyde
- Packaging
- 50mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- FD154398
- Product name
- 6-(Dimethylamino)-2-naphthaldehyde
- Packaging
- 50mg
- Price
- $71
- Updated
- 2021/12/16
- Product number
- FD154398
- Product name
- 6-(Dimethylamino)-2-naphthaldehyde
- Packaging
- 100mg
- Price
- $124
- Updated
- 2021/12/16
- Product number
- W3786
- Product name
- 6-(Dimethylamino)-2-naphthaldehyde
- Packaging
- 250mg
- Price
- $211
- Updated
- 2021/12/16
- Product number
- FD154398
- Product name
- 6-(Dimethylamino)-2-naphthaldehyde
- Packaging
- 250mg
- Price
- $247.5
- Updated
- 2021/12/16
6-DIMETHYLAMINO-2-NAPHTHALDEHYDE Chemical Properties,Usage,Production
Synthesis
5043-03-8
68-12-2
173471-71-1
1. 11.4 g of 6-bromo-N,N-dimethylnaphthalen-2-amine (Intermediate 1) was dissolved in 50 mL of anhydrous tetrahydrofuran and cooled to -78 °C under nitrogen protection. 2. 27.5 mL of n-butyllithium (2.5 M n-hexane solution) was added dropwise slowly, and the reaction was stirred at a temperature of -78 °C for 30 min. 3. 5.5 mL of N,N- dimethylformamide (DMF) to the reaction system, the reaction mixture was gradually warmed to room temperature and stirring was continued for 15 min. 4. The reaction solution was adjusted to acidic (pH<7) with 1 M hydrochloric acid and stirred for 15 min at room temperature. 5. The reaction solution was adjusted to basic (pH>7) with ammonia, and the resulting solid was collected by filtration. 6. The solid was washed several times with deionized water, and dried to afford 8.6 g of the yellow solid product 6-( dimethylamino)-2-naphthalenal in 93.5% yield.
References
[1] Patent: CN104140381, 2018, B. Location in patent: Paragraph 0057-0058
[2] Organic Letters, 2012, vol. 14, # 10, p. 2598 - 2601
[3] Patent: CN108218743, 2018, A. Location in patent: Paragraph 0040; 0045-0047
[4] Journal of the American Chemical Society, 2017, vol. 139, # 38, p. 13393 - 13403
[5] Chemistry - A European Journal, 2016, vol. 22, # 40, p. 14166 - 14170
6-DIMETHYLAMINO-2-NAPHTHALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
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