ChemicalBook > CAS DataBase List > 8-METHYLTHIOGUANOSINE
8-METHYLTHIOGUANOSINE
- Product Name
- 8-METHYLTHIOGUANOSINE
- CAS No.
- 2104-66-7
- Chemical Name
- 8-METHYLTHIOGUANOSINE
- Synonyms
- 8-METHYLTHIOGUANOSINE;Guanosine, 8-(methylthio)-
- CBNumber
- CB3198568
- Molecular Formula
- C11H15N5O5S
- Formula Weight
- 329.33
- MOL File
- Mol file
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8-METHYLTHIOGUANOSINE Property
- Density
- 2.12±0.1 g/cm3(Predicted)
- pka
- 9.17±0.20(Predicted)
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8-METHYLTHIOGUANOSINE Chemical Properties,Usage,Production
Uses
8-(Methylthio)guanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
References
[1] Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51. DOI:10.1073/pnas.0631696100
8-METHYLTHIOGUANOSINE Preparation Products And Raw materials
Raw materials
Preparation Products
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8-METHYLTHIOGUANOSINE Suppliers
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- Russia
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