4-N-BUTOXYBENZYL BROMIDE
- Product Name
- 4-N-BUTOXYBENZYL BROMIDE
- CAS No.
- 2417-74-5
- Chemical Name
- 4-N-BUTOXYBENZYL BROMIDE
- Synonyms
- 4-BUTOXYBENZYL BROMIDE;4-N-BUTOXYBENZYL BROMIDE;Benzene, 1-(bromomethyl)-4-butoxy-
- CBNumber
- CB3201228
- Molecular Formula
- C11H15BrO
- Formula Weight
- 243.14
- MOL File
- 2417-74-5.mol
N-Bromosuccinimide Price
- Product number
- B688490
- Product name
- 1-(Bromomethyl)-4-butoxy-benzene
- Packaging
- 25g
- Price
- $2145
- Updated
- 2021/12/16
- Product number
- CHM0290163
- Product name
- 4-N-BUTOXYBENZYL BROMIDE
- Purity
- 98.00%
- Packaging
- 5MG
- Price
- $503.16
- Updated
- 2021/12/16
4-N-BUTOXYBENZYL BROMIDE Chemical Properties,Usage,Production
Uses
4-N-BUTOXYBENZYL BROMIDE is an intermediate used to prepare 6-(dimethylamino)-2-(trifluoromethyl)-9-(substituted benzyl)-9H-purines with antirhinovirus activity. It is also used in the synthesis of alkyl derivatives of the glycopeptide antibiotic A40926 and their amides with antibacterial acitivity.
Synthesis
The synthesis of 4-N-BUTOXYBENZYL BROMIDE is as follows:Under the protection of nitrogen,Add 40g of compound 5-1 to a 1L reaction flask,50g hydrogen bromide solution (hydrogen bromide concentration is 40wt%) and 500mL toluene,After fully dissolving, control the temperature between 110130,The reaction was stirred for 5h.Add 300 mL of ethyl acetate and 400 mL of water to the reaction solution for extraction,Collect the ethyl acetate layer, add anhydrous sodium sulfate for drying, then concentrate,Obtain 40 g of white solid (compound 6-1),The yield was 74.12%.
4-N-BUTOXYBENZYL BROMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
4-N-BUTOXYBENZYL BROMIDE Suppliers
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