2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID
- Product Name
- 2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID
- CAS No.
- 21801-79-6
- Chemical Name
- 2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID
- Synonyms
- ASISCHEM C71528;BUTTPARK 9\05-56;3-Carboxy-2-methylimidazo[1,2-a]pyridine;2-methyl-3-imidazo[1,2-a]pyridinecarboxylate;2-a)pyridine-3-carboxylicacid,2-methyl-imidazo(;2-Methyl-imidazo[1,2-a]pyridin-3-carboxylic acid;2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID;IMidazo[1,2-a]pyridine-3-carboxylic acid, 2-Methyl-;2-Methylimidazoó1,2-a!pyridine-3-carboxylic acid, 97%;2-Methylimidazo[1,2-a]pyridine-3-carboxylic acid ,97%
- CBNumber
- CB3201309
- Molecular Formula
- C9H8N2O2
- Formula Weight
- 176.17
- MOL File
- 21801-79-6.mol
2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID Property
- Melting point:
- 140 °C
- Boiling point:
- 170°C
- Density
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- -0.55±0.41(Predicted)
- Appearance
- White to off-white Solid
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-36-22
- Safety Statements
- 26-36/37/39-22
- HazardClass
- IRRITANT
- HS Code
- 29339900
- Toxicity
- mouse,LD50,intraperitoneal,600mg/kg (600mg/kg),BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLDBEHAVIORAL: IRRITABILITYBEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY),Journal of Medicinal Chemistry. Vol. 12, Pg. 122, 1969.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M643280
- Product name
- 2-methylimidazo[1,2-a]pyridine-3-carboxylicacid
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- J96646
- Product name
- 2-Methylimidazo[1,2-a]pyridine-3-carboxylicacid
- Packaging
- 1g
- Price
- $65
- Updated
- 2021/12/16
- Product number
- J96646
- Product name
- 2-Methylimidazo[1,2-a]pyridine-3-carboxylicacid
- Packaging
- 250mg
- Price
- $22
- Updated
- 2021/12/16
- Product number
- OR9488
- Product name
- 2-Methylimidazo[1,2-a]pyridine-3-carboxylicacid
- Packaging
- 250mg
- Price
- $23
- Updated
- 2021/12/16
- Product number
- Y8284
- Product name
- 2-Methylimidazo[1,2-a]pyridine-3-carboxylicacid
- Packaging
- 250mg
- Price
- $29
- Updated
- 2021/12/16
2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID Chemical Properties,Usage,Production
Chemical Properties
Pink solid
Synthesis
2549-19-1
21801-79-6
To a stirred ethyl 2-methylimidazo[1,2-a]pyridine-3-carboxylate (2.00 g) solution of ethanol/water (1:1, 30 mL) was added lithium hydroxide (4.00 g) and the reaction was stirred for 4 hours at room temperature. Upon completion of the reaction, the reaction mixture was concentrated to half of the original volume, followed by the slow addition of 6N hydrochloric acid at 0 °C and adjusting the pH to 6. The precipitated solid was collected by filtration and dried in a vacuum oven to afford 2-methylimidazo[1,2-a]pyridine-3-carboxylic acid (1.53 g, 88% yield) as an off-white solid.ESI-MS analysis showed the molecular ion peaks as 177 [M + H]+.
References
[1] Journal of Medicinal Chemistry, 2012, vol. 55, # 17, p. 7525 - 7545
[2] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 15, p. 4223 - 4232
[3] Farmaco, Edizione Scientifica, 1982, vol. 37, # 1, p. 22 - 35
[4] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 5, p. 1870 - 1873
[5] Journal of Medicinal Chemistry, 2014, vol. 57, # 12, p. 5293 - 5305
2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID manufacturers
- Product
- 2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID 21801-79-6
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-07
- Product
- 4-Bromobenzaldehyde 1122-91-4
- Price
- US $1.00/ASSAYS
- Min. Order
- 1ASSAYS
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-07