ChemicalBook > CAS DataBase List > Olivetol

Olivetol

Product Name
Olivetol
CAS No.
500-66-3
Chemical Name
Olivetol
Synonyms
1,3-Benzenediol, 5-pentyl-;5-PENTYLRESORCINOL;3,5-dihydroxyamylbenzene;Olivetol Powder;5-pentylbenzene-1,3-diol;CL213;ivetoL;Olidol;OLIVETOL;Oilvetol
CBNumber
CB3204779
Molecular Formula
C11H16O2
Formula Weight
180.24
MOL File
500-66-3.mol
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Olivetol Property

Melting point:
46-48 °C(lit.)
Boiling point:
164 °C
Density 
1.068±0.06 g/cm3(Predicted)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
9.59±0.10(Predicted)
color 
Colourless to Beige
Stability:
Light Sensitive
InChI
InChI=1S/C11H16O2/c1-2-3-4-5-9-6-10(12)8-11(13)7-9/h6-8,12-13H,2-5H2,1H3
InChIKey
IRMPFYJSHJGOPE-UHFFFAOYSA-N
SMILES
C1(O)=CC(CCCCC)=CC(O)=C1
CAS DataBase Reference
500-66-3(CAS DataBase Reference)
NIST Chemistry Reference
1,3-Benzenediol, 5-pentyl-(500-66-3)
EPA Substance Registry System
Olivetol (500-66-3)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/39
WGK Germany 
3
RTECS 
VH2880000
HS Code 
2907290090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
152633
Product name
Olivetol
Purity
95%
Packaging
1g
Price
$63.8
Updated
2024/03/01
TRC
Product number
O533000
Product name
Olivetol
Packaging
5g
Price
$90
Updated
2021/12/16
TRC
Product number
O533000
Product name
Olivetol
Packaging
25g
Price
$250
Updated
2021/12/16
Matrix Scientific
Product number
084690
Product name
5-Pentylbenzene-1,3-diol
Purity
97%
Packaging
25g
Price
$468
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
60838
Product name
Olivetol
Packaging
2.5g
Price
$595
Updated
2021/12/16
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Olivetol Chemical Properties,Usage,Production

Chemical Properties

Olivetol is an off-white crystals or olive to light purple waxy solid. Forms monohydrate (melting point: 102-106°F). Olivetol is a member of the class of resorcinols that is resorcinol in which the hydrogen at position 5 is replaced by a pentyl group. It has a role as a lichen metabolite.

Physical properties

light purple to brown crystalline mass.

Uses

Olivetol was used as a template molecule in the synthesis of molecularly imprinted polymer (MIP). It was also used as an inhibitor of (S)-mephenytoin 4'-hydroxylase activity of recombinant CYP2C19.

Application

Olivetol is a precursor in various syntheses of tetrahydrocannabinol.

Preparation

olivetol can also be formed through hydrolysis of intermediate polyketide CoAs or spontaneous cyclization.

Definition

ChEBI: Olivetol is a member of the class of resorcinols that is resorcinol in which the hydrogen at position 5 is replaced by a pentyl group. It has a role as a lichen metabolite.

Synthesis Reference(s)

The Journal of Organic Chemistry, 42, p. 3456, 1977 DOI: 10.1021/jo00441a036

General Description

Olivetol appears as off-white crystals or olive to light purple waxy solid. Forms monohydrate (melting point: 102-106°F). (NTP, 1992)

Air & Water Reactions

Sensitive to air. Insoluble in water.

Reactivity Profile

Olivetol is incompatible with acid chlorides, acid anhydrides and oxidizing agents.

Fire Hazard

Olivetol is probably combustible.

Biological Activity

Olivetol (5-Pentylresorcinol, 5-n-Amylresorcinol) is a naturally occurring organic compound being a precursor in various syntheses of tetrahydrocannabinol. It acts as a competitive inhibitor of the cannabinoid receptors CB1 and CB2.

Safety

Olivetol is still a very new product. It has not been researched nearly enough to prove it's safe to use. So far, no one has reported any adverse side effects as far as we know. Until more information is available, carefully control your THC intake instead of relying on an untested gelcap.

Mode of action

When you look at olivetol's molecular structure, it'll look very familiar. It's as if someone took a THC molecule and sliced it in two. Olivetol, like THC, works by binding with the CB1 receptors that exist all over your body and brain. But, olivetol is thought to be smaller and stickier than THC, so that helps it reduce a raging high in two ways. First, it slips into any open receptors before THC can get there to block them—so you won't get any higher. Second, it bumps into THC molecules that are already lodged in a CB1 receptor to knock them loose and take their place. That's how it brings you down.
According to numerous personal accounts, olivetol works, but we don't know exactly how it does so. More research and investigation is needed, but in theory it's very similar to how Narcan acts to reverse opiate overdoses.

Olivetol Preparation Products And Raw materials

Raw materials

Preparation Products

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Olivetol Suppliers

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View Lastest Price from Olivetol manufacturers

Hebei Longbang Technology Co., Ltd
Product
Olivetol 500-66-3
Price
US $6.00/kg
Min. Order
1kg
Purity
More than 99%
Supply Ability
2000KG/Month
Release date
2024-05-10
HebeiShuoshengImportandExportco.,Ltd
Product
Olivetol 500-66-3
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-09
Dorne Chemical Technology co. LTD
Product
Olivetol 500-66-3
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
1000kg
Release date
2024-05-20

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