PROSTAGLANDIN B1
- Product Name
- PROSTAGLANDIN B1
- CAS No.
- 13345-51-2
- Chemical Name
- PROSTAGLANDIN B1
- Synonyms
- PGB1;PGE1-278;15-epi-PGB1;PROSTAGLANDIN B1;PROSTAGLANDINS B1;Prostaglandin E1-278;PGB1 (Prostaglandin B1);Prostaglandin Impurity B;(-)-(E)-Prostaglandin E1-278;Alprostadil (Prostaglandin E1) Impurity
- CBNumber
- CB3206425
- Molecular Formula
- C20H32O4
- Formula Weight
- 336.47
- MOL File
- 13345-51-2.mol
PROSTAGLANDIN B1 Property
- Melting point:
- 69-71°C
- Boiling point:
- 531.4±43.0 °C(Predicted)
- Density
- 1.101±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- acetone: 20 mg/mL, clear, colorless to very faintly yellow
- form
- powder
- pka
- 4.77±0.10(Predicted)
- color
- white to light yellow
- biological source
- synthetic
- BRN
- 2004447
- Stability:
- Light Sensitive
N-Bromosuccinimide Price
- Product number
- 1578554
- Product name
- Prostaglandin B1
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 25mg
- Price
- $3320
- Updated
- 2024/03/01
- Product number
- 11110
- Product name
- Prostaglandin B1
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $25
- Updated
- 2024/03/01
- Product number
- 11110
- Product name
- Prostaglandin B1
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $107
- Updated
- 2024/03/01
- Product number
- 11110
- Product name
- Prostaglandin B1
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $186
- Updated
- 2024/03/01
- Product number
- 11110
- Product name
- Prostaglandin B1
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $807
- Updated
- 2024/03/01
PROSTAGLANDIN B1 Chemical Properties,Usage,Production
Uses
Prostaglandin B1 is a novel microbial biopolymer which has been shown to improve the longevity of type 2 diabetic rodents. Oligomers of prostaglandin B1 inhibit arachidonic acid mobilization in human neutrophils and endothelial cells.
Definition
ChEBI: Prostaglandin B1 is a member of the class of prostaglandins B that is prosta-8(12),13-dien-1-oic acid carrying oxo and hydroxy substituents at positions 9 and 15 respectively (the 13E,15S-stereoisomer). It has a role as a human metabolite. It is a conjugate acid of a prostaglandin B1(1-).
Biological Activity
Prostaglandin B1 (PGB1) is a metabolic product of PGE1 dehydration. It is known to specifically bind to peroxisome proliferator-activated receptor-γ. By this, PGB1 mediates f at accumulation and metabolism. Oligomerization of PGB1 potentiates its anti-oxidative property.
Enzyme inhibitor
This eicosanoid (FWB1 (free-acid) = 336.47 g/mol; CAS 13345-51-2, for PGB1, and 39306-29-1, for Bx) is a metabolite of prostaglandin E1: prostaglandin Bx is an oligomer of prostaglandin B1. The X-ray crystal structure of prostaglandin B1 suggests this prostaglandin has an unusual L-shaped configuration, with the a and w side chains roughly perpendicular to one another. The 15-hydroxyl group, which is normally directed away from the centroid of the prostaglandin in the standard hairpin mod+el, is turned inward in prostaglandin B1. Target (s) : FoF1 ATPase, or H-transporting two-sector ATPase, inhibited by prostaglandin Bx; 15- hydroxyprostaglandin dehydrogenase; phospholipase A2, inhibited by prostaglandin Bx.
PROSTAGLANDIN B1 Preparation Products And Raw materials
Raw materials
Preparation Products
PROSTAGLANDIN B1 Suppliers
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