3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone

Product Name: 3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone
CAS No.: 351986-85-1
Chemical Name: 3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone
Synonyms: Vacuolin-1;Vacuolin-1 ，S6912;Vacuolin-1, 10 mM in DMSO;Vacuolin-1 - CAS 351986-85-1 - Calbiochem;Diethylcarbamazine Impurity 1（Diethylcarbamazine EP Impurity A）;4-(2-(3-Iodobenzylidene)hydrazinyl)-6-morpholino-N,N-diphenyl-1,3,5-triazin-2-amine;3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone;(E)-4-(2-(3-iodobenzylidene)hydrazinyl)-6-Morpholino-N,N-diphenyl-1,3,5-triazin-2-aMine;Benzaldehyde, 3-iodo-, 2-[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone;4-[(2E)-2-(3-iodobenzylidene)hydrazinyl]-6-(morpholin-4-yl)-N,N-diphenyl-1,3,5-triazin-2-amine
CBNumber: CB32096419
Molecular Formula: C26H24IN7O
Formula Weight: 577.42
MOL File: 351986-85-1.mol

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3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone Property

Boiling point:: 719.7±70.0 °C(Predicted)
Density: 1.53±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO:18.33(Max Conc. mg/mL);31.74(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:7):0.12(Max Conc. mg/mL);0.21(Max Conc. mM)
DMF:3.0(Max Conc. mg/mL);5.2(Max Conc. mM)
form: White solid
pka: 10.74±0.10(Predicted)
color: White to off-white
Appearance: white powder

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Safety

Hazard Codes: Xn
Risk Statements: 22

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 673000
Product name: Vacuolin-1 - CAS 351986-85-1 - Calbiochem
Packaging: 10mg
Price: $192
Updated: 2025/07/31

Cayman Chemical

Product number: 20425
Product name: Vacuolin-1
Purity: ≥95%
Packaging: 1mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 20425
Product name: Vacuolin-1
Purity: ≥95%
Packaging: 5mg
Price: $98
Updated: 2024/03/01

Cayman Chemical

Product number: 20425
Product name: Vacuolin-1
Purity: ≥95%
Packaging: 10mg
Price: $161
Updated: 2024/03/01

Cayman Chemical

Product number: 20425
Product name: Vacuolin-1
Packaging: 25mg
Price: $353
Updated: 2024/03/01

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3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone Chemical Properties,Usage,Production

Description

Vacuolin-1 is a triazine-based small chemical, a specific inhibitor of Ca²⁺–dependent lysosomal exocytosis. The inhibitor penetrates the cell, blocking the fusion of lysosomes with the plasma membrane. Vacuolin-1 does not affect other membrane-bound organelles and endocytic or secretory traffic. The inhibitor is widely used in studies on the release of lysosomal content and the modulation of autophagy.

Uses

Vacuolin-1 is a cell-permeable triazine that inhibits Ca2+-dependent fusion of lysosomes to the cell membrane inhibiting release of lysosomal content.

Biological Activity

Cell permeable: yes', 'Primary Target
Ca2+-dependent fusion of lysosomes with the plasma membrane', 'Product does not compete with ATP.', 'Reversible: no

3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone Suppliers

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351986-85-1, 3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazoneRelated Search:

HATU

4-[(2E)-2-(3-iodobenzylidene)hydrazinyl]-6-(morpholin-4-yl)-N,N-diphenyl-1,3,5-triazin-2-amine

3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone

Vacuolin-1

(E)-4-(2-(3-iodobenzylidene)hydrazinyl)-6-Morpholino-N,N-diphenyl-1,3,5-triazin-2-aMine

Vacuolin-1 - CAS 351986-85-1 - Calbiochem

Benzaldehyde, 3-iodo-, 2-[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone

4-(2-(3-Iodobenzylidene)hydrazinyl)-6-morpholino-N,N-diphenyl-1,3,5-triazin-2-amine

Inhibitor,Fab1,Vacuolin1,Autophagy,Vacuolin 1,PIKfyve,membrane repair,Vacuolin-1,inhibit,exocytosis,HeLa cells

Diethylcarbamazine Impurity 1（Diethylcarbamazine EP Impurity A）

Vacuolin-1, 10 mM in DMSO

Vacuolin-1 ，S6912

351986-85-1

C26H24IN7O