3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone

Product Name: 3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone
CAS No.: 351986-85-1
Chemical Name: 3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone
Synonyms: Vacuolin-1;Vacuolin-1 ，S6912;Vacuolin-1, 10 mM in DMSO;Vacuolin-1 - CAS 351986-85-1 - Calbiochem;Diethylcarbamazine Impurity 1（Diethylcarbamazine EP Impurity A）;4-(2-(3-Iodobenzylidene)hydrazinyl)-6-morpholino-N,N-diphenyl-1,3,5-triazin-2-amine;3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone;(E)-4-(2-(3-iodobenzylidene)hydrazinyl)-6-Morpholino-N,N-diphenyl-1,3,5-triazin-2-aMine;Benzaldehyde, 3-iodo-, 2-[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone;4-[(2E)-2-(3-iodobenzylidene)hydrazinyl]-6-(morpholin-4-yl)-N,N-diphenyl-1,3,5-triazin-2-amine
CBNumber: CB32096419
Molecular Formula: C26H24IN7O
Formula Weight: 577.42
MOL File: 351986-85-1.mol

More

Less

3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone Property

Boiling point:: 719.7±70.0 °C(Predicted)
Density: 1.53±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO:18.33(Max Conc. mg/mL);31.74(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:7):0.12(Max Conc. mg/mL);0.21(Max Conc. mM)
DMF:3.0(Max Conc. mg/mL);5.2(Max Conc. mM)
form: White solid
pka: 10.74±0.10(Predicted)
color: White to off-white
Appearance: white powder
InChIKey: JMEJTSRAQUFNOP-TURZUDJPSA-N
SMILES: Ic1cc(ccc1)\C=N\Nc2nc(nc(n2)N(c5ccccc5)c4ccccc4)N3CCOCC3

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: WGK 3
Storage Class: 11 - Combustible Solids

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 673000
Product name: Vacuolin-1 - CAS 351986-85-1 - Calbiochem
Packaging: 10mg
Price: $192
Updated: 2025/07/31

Cayman Chemical

Product number: 20425
Product name: Vacuolin-1
Purity: ≥95%
Packaging: 1mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 20425
Product name: Vacuolin-1
Purity: ≥95%
Packaging: 5mg
Price: $98
Updated: 2024/03/01

Cayman Chemical

Product number: 20425
Product name: Vacuolin-1
Purity: ≥95%
Packaging: 10mg
Price: $161
Updated: 2024/03/01

Cayman Chemical

Product number: 20425
Product name: Vacuolin-1
Packaging: 25mg
Price: $353
Updated: 2024/03/01

More

Less

3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone Chemical Properties,Usage,Production

Description

Vacuolin-1 is a triazine-based small chemical, a specific inhibitor of Ca²⁺–dependent lysosomal exocytosis. The inhibitor penetrates the cell, blocking the fusion of lysosomes with the plasma membrane. Vacuolin-1 does not affect other membrane-bound organelles and endocytic or secretory traffic. The inhibitor is widely used in studies on the release of lysosomal content and the modulation of autophagy.

Uses

Vacuolin-1 is a cell-permeable triazine that inhibits Ca2+-dependent fusion of lysosomes to the cell membrane inhibiting release of lysosomal content.

Biological Activity

Cell permeable: yes', 'Primary Target
Ca2+-dependent fusion of lysosomes with the plasma membrane', 'Product does not compete with ATP.', 'Reversible: no

3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone Suppliers

China 85 Switzerland 1 United States 7 Global 93

Beijing Ouhe Technology Co., Ltd

Tel: 010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 11776
Advantage: 60

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185;
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3505
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-400-164-7117 18317119277
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 40000
Advantage: 60

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4800
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

Shanghai Rechem science Co., Ltd.

Tel: 021-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2961
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Chuzhou KeMail Chemical Technology Co., Ltd

Tel: 0550-5196001 15000891977
Fax: 0550-5196001
Email: wj520wjxby@126.com
Country: China
ProdList: 1945
Advantage: 55

351986-85-1, 3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazoneRelated Search:

HATU

4-[(2E)-2-(3-iodobenzylidene)hydrazinyl]-6-(morpholin-4-yl)-N,N-diphenyl-1,3,5-triazin-2-amine

3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone

Vacuolin-1

(E)-4-(2-(3-iodobenzylidene)hydrazinyl)-6-Morpholino-N,N-diphenyl-1,3,5-triazin-2-aMine

Vacuolin-1 - CAS 351986-85-1 - Calbiochem

Benzaldehyde, 3-iodo-, 2-[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone

4-(2-(3-Iodobenzylidene)hydrazinyl)-6-morpholino-N,N-diphenyl-1,3,5-triazin-2-amine

Inhibitor,Fab1,Vacuolin1,Autophagy,Vacuolin 1,PIKfyve,membrane repair,Vacuolin-1,inhibit,exocytosis,HeLa cells

Diethylcarbamazine Impurity 1（Diethylcarbamazine EP Impurity A）

Vacuolin-1, 10 mM in DMSO

Vacuolin-1 ，S6912

351986-85-1

C26H24IN7O