ChemicalBook > CAS DataBase List > Hydroxyhomosildenafil

Hydroxyhomosildenafil

Product Name
Hydroxyhomosildenafil
CAS No.
139755-85-4
Chemical Name
Hydroxyhomosildenafil
Synonyms
Lodenafil;Hydroxyhomosildenafil;Lodenafil, 10 mM in DMSO;Hydroxyhomosildenafil in Methanol;Lodenafil (Hydroxyhomosildenafil);Hydroxyhomosildenafil Solution, 100μg/mL;Hydroxyhomosildenafil, Sildenafil analog;inhibit,Phosphodiesterase (PDE),Lodenafil,Inhibitor;5-[2-ethoxy-5-[4-(2-hydroxyethyl)piperazin-1-yl]sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one;5-(2-Ethoxy-5-((4-(2-hydroxyethyl)piperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4，3-d]pyrimidin-7(6H)-one
CBNumber
CB32104134
Molecular Formula
C23H32N6O5S
Formula Weight
504.6
MOL File
139755-85-4.mol
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Hydroxyhomosildenafil Property

Melting point:
183-185?C
Density 
1.42±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
10.05±0.20(Predicted)
color 
White to Light Yellow
InChIKey
NEYKRKVLEWKOBI-UHFFFAOYSA-N
SMILES
C1(C2=CC(S(N3CCN(CCO)CC3)(=O)=O)=CC=C2OCC)NC(=O)C2N(C)N=C(CCC)C=2N=1
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Safety

HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological
Product number
279423
Product name
Hydroxyhomo Sildenafil
Packaging
5mg
Price
$602
Updated
2021/12/16
TRC
Product number
H942840
Product name
HydroxyhomoSildenafil
Packaging
2mg
Price
$110
Updated
2021/12/16
ChemScene
Product number
CS-0081887
Product name
Lodenafil
Purity
99.73%
Packaging
5mg
Price
$150
Updated
2021/12/16
ChemScene
Product number
CS-0081887
Product name
Lodenafil
Purity
99.73%
Packaging
10mg
Price
$250
Updated
2021/12/16
ChemScene
Product number
CS-0081887
Product name
Lodenafil
Purity
99.73%
Packaging
50mg
Price
$850
Updated
2021/12/16
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Hydroxyhomosildenafil Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

A Sildenafil (S435000) analog, enhances male sexual function.

in vivo

Lodenafil (10 mg, p.o., male Beagle dogs, PK assay) shows a T1/2 of 4.32 h, Cmax of 1357 ng/mL, AUC0-24 of 9091 ng/h/mL[1].

IC 50

PDE5

Hydroxyhomosildenafil Preparation Products And Raw materials

Raw materials

Preparation Products

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Hydroxyhomosildenafil Suppliers

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139755-85-4, HydroxyhomosildenafilRelated Search:

Thiosildenafil tadalafi Sildenafil citrate Sildenafil

  • Hydroxyhomosildenafil
  • 5-[2-Ethoxy-5-[[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl]phenyl]-1,6-dihydro-1-Methyl-3-propyl-7H-pyrazolo[4,3-d]pyriMidin-7-one
  • Lodenafil
  • 5-[2-ethoxy-5-[4-(2-hydroxyethyl)piperazin-1-yl]sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one
  • 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-[[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-
  • Hydroxyhomosildenafil Solution, 100μg/mL
  • 5-(2-Ethoxy-5-((4-(2-hydroxyethyl)piperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4，3-d]pyrimidin-7(6H)-one
  • Lodenafil (Hydroxyhomosildenafil)
  • inhibit,Phosphodiesterase (PDE),Lodenafil,Inhibitor
  • 5-(2-Ethoxy-5-((4-(2-hydroxyethyl)piperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one? (Sildenafil Impurity)
  • Hydroxyhomosildenafil in Methanol
  • Hydroxyhomosildenafil, Sildenafil analog
  • Lodenafil, 10 mM in DMSO
  • 139755-85-4
  • C23H32N6O5S
  • Aromatics
  • Drug Analogues
  • Heterocycles
  • Sulfur & Selenium Compounds