(2S,3R,4E)-2-Amino-4-hexadecene-1,3-diol Property

Boiling point:

419.6±45.0 °C(Predicted)

Density 

0.950±0.06 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

DMF: 10 mg/ml; DMSO: 2 mg/ml; Ethanol: miscible

form 

A crystalline solid

pka

11.80±0.45(Predicted)

Hazard and Precautionary Statements (GHS)

(2S,3R,4E)-2-Amino-4-hexadecene-1,3-diol Chemical Properties,Usage,Production

Uses

C16-Sphingosine has shown cytotoxicity towards human colon cancer cells.

Definition

ChEBI: Hexadecasphing-4-enine is a sphingoid that is the C16 analogue of sphingosine. It has a role as a mouse metabolite. It is a sphingoid and an aminodiol. It is a conjugate base of a hexadecasphing-4-enine(1+).

Biological Activity

Sphingosine is implicated in negative regulation of cell proliferation and stimulation of apoptosis. It has a potential to control the activities of phospholipases, protein kinases, ion channels, cannabinoid receptor type 1 (CB-1) receptors and steroidogenic factor 1 (SF-1) receptors.