2-Methyl-5,7-dihydroxychromone
- Product Name
- 2-Methyl-5,7-dihydroxychromone
- CAS No.
- 1013-69-0
- Chemical Name
- 2-Methyl-5,7-dihydroxychromone
- Synonyms
- Noreugenin;reugenin;Noreugenin, 10 mM in DMSO;2-Methyl-5,7-dihydroxychromone;5,7-dihydroxy-2-methylchromen-4-one;5,7-Dihydroxy-2-methyl-4H-1-benzopyran-4-one;2-Methyl-5,7-dihydroxy-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one,5,7-dihydroxy-2-methyl-
- CBNumber
- CB32197071
- Molecular Formula
- C10H8O4
- Formula Weight
- 192.17
- MOL File
- 1013-69-0.mol
2-Methyl-5,7-dihydroxychromone Property
- Melting point:
- 279 °C
- Boiling point:
- 394.6±42.0 °C(Predicted)
- Density
- 1.456±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 250 mg/mL (1300.93 mM); Water: < 0.1 mg/mL (insoluble)
- form
- Solid
- pka
- 6.58±0.40(Predicted)
- color
- White to off-white
- InChI
- InChI=1S/C10H8O4/c1-5-2-7(12)10-8(13)3-6(11)4-9(10)14-5/h2-4,11,13H,1H3
- InChIKey
- NCUJRUDLFCGVOE-UHFFFAOYSA-N
- SMILES
- C1(C)OC2=CC(O)=CC(O)=C2C(=O)C=1
N-Bromosuccinimide Price
- Product number
- FN42576
- Product name
- Noreugenin
- Packaging
- 1mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- FN42576
- Product name
- Noreugenin
- Packaging
- 2mg
- Price
- $340
- Updated
- 2021/12/16
- Product number
- CHM0299002
- Product name
- 5,7-DIHYDROXY-2-METHYL-4H-1-BENZOPYRAN-4-ONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.23
- Updated
- 2021/12/16
- Product number
- FN42576
- Product name
- Noreugenin
- Packaging
- 5mg
- Price
- $550
- Updated
- 2021/12/16
- Product number
- FN42576
- Product name
- Noreugenin
- Packaging
- 10mg
- Price
- $850
- Updated
- 2021/12/16
2-Methyl-5,7-dihydroxychromone Chemical Properties,Usage,Production
Uses
Noreugenin, 5,7-dihydroxy-2-methyl-4H-chromen-4-one, is a new chromone from Aloe arborescens. (Amaryllidaceae)[1].
Definition
ChEBI: Noreugenin is a member of the class of chromones in which the 1,4-benzopyrone skeleton is substituted with a methyl group at position 2 and with hydroxy groups at positions 5 and 7. A natural product, it is found in Pisonia aculeata. It has a role as a plant metabolite. It is a member of chromones and a member of resorcinols. It is a conjugate acid of a noreugenin(1-).
Synthesis
1162-81-8
1013-69-0
The general procedure for the synthesis of 5,7-dihydroxy-2-methyl-4H-benzopyran-4-one from the compound (CAS:1162-81-8) is as follows: 2-methyl-3-acetyl-5,7-diacetoxychromanone (15.9 g, 0.05 mol) was placed in a 1 L three-necked flask and 400 mL of sodium carbonate solution (10 mL) was added. The mixture was heated to reflux for 2 hours. After the reaction was completed, it was cooled to room temperature and filtered to remove insoluble material. The filtrate was adjusted to pH 7~8 with hydrochloric acid, at which time a large amount of solid precipitated. The solution was further cooled to below 10°C, filtered and the solids were collected. The filter cake was dried under vacuum at 40 °C for 4 h to give 8.98 g of off-white solid powder in 93.6% yield. The structure of the final product 2-methyl-5,7-dihydroxychromone was confirmed by 1H-NMR and mass spectrometry.
References
[1] Wang Y, et al. Aspergchromones A and B, two new polyketides from the marine sponge-associated fungus Aspergillus sp. SCSIO XWS03F03. J Asian Nat Prod Res. 2017 Jul;19(7):684-690. DOI:10.1080/14786419.2014.951931
2-Methyl-5,7-dihydroxychromone Preparation Products And Raw materials
Raw materials
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View Lastest Price from 2-Methyl-5,7-dihydroxychromone manufacturers
- Product
- 2-Methyl-5,7-dihydroxychromone 1013-69-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000KG
- Release date
- 2024-07-16
- Product
- Noreugenin 1013-69-0
- Price
- US $9.80/KG
- Min. Order
- 1KG
- Purity
- ＞98%HPLC
- Supply Ability
- 20 tons
- Release date
- 2020-02-06