1-Methoxy-9H-carbazole-3-carbaldehyde

Product Name: 1-Methoxy-9H-carbazole-3-carbaldehyde
CAS No.: 723-97-7
Chemical Name: 1-Methoxy-9H-carbazole-3-carbaldehyde
Synonyms: Murrayanine;1-Methoxy-9H-carbazole-3-carbaldehyde;9H-Carbazole-3-carboxaldehyde, 1-methoxy-
CBNumber: CB32223213
Molecular Formula: C14H11NO2
Formula Weight: 225.24
MOL File: 723-97-7.mol

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1-Methoxy-9H-carbazole-3-carbaldehyde Property

Melting point:: 168°C
Boiling point:: 466.4±25.0 °C(Predicted)
Density: 1.312±0.06 g/cm3(Predicted)
pka: 16.49±0.30(Predicted)

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Hazard and Precautionary Statements (GHS)

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1-Methoxy-9H-carbazole-3-carbaldehyde Chemical Properties,Usage,Production

Description

This simple carbazole alkaloid is found in the stem bark of Mu"aya koenigii Spreng. It is best purified by sublimation of the crude base when it yields colour_x0002_less crystals. The ultraviolet spectrum in ethanol has absorption maxima at 238, 247,274,289 and 335 mJJ.. The structure has been shown to be 3-formyl-lmethoxycarbazole by spectroscopic methods and synthesis. It yields an oxime, m.p. l55-6°C; a picrate, m.p. 198-2000 C and the 2:4-dinitrophenylhydrazone, m.p. > 300°C. The N-methyl derivative forms colourless needles from C6H6- light petroleum, m.p. l48-9°C. When subjected to Wolff-Kishner reduction, the alkaline phase yields l-hydroxy-3-methyl-carbazole.

Uses

Murrayanine is a carbazole alkaloid. Murrayanine suppresses the proliferation and metastasis of human breast cancer cells via induction of apoptosis and inhibition of RANK/RANKL signaling pathway.

Definition

ChEBI: A natural product found in Clausena harmandiana.

References

Chakraborty, Barman, Bose., Tetrahedron, 21, 681 (1965)
Synthesis: Crum, Sprague., Chern. Cornrnun., 417 (1966)
Chakraborty, Chowdhury., J. Org. Chern., 33, 1265 (1968)

1-Methoxy-9H-carbazole-3-carbaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Methoxy-9H-carbazole-3-carbaldehyde Suppliers

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723-97-7, 1-Methoxy-9H-carbazole-3-carbaldehydeRelated Search:

1-Methoxy-9H-carbazole-3-carbaldehyde

Murrayanine

9H-Carbazole-3-carboxaldehyde, 1-methoxy-

723-97-7