(2R,3S)-2-Hydroxy-3-methylpentanoic acid Property

Boiling point:

251.3±13.0 °C(Predicted)

Density 

1.097±0.06 g/cm3(Predicted)

pka

3.89±0.31(Predicted)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

(2R,3S)-2-Hydroxy-3-methylpentanoic acid Chemical Properties,Usage,Production

Definition

ChEBI: (2R,3S)-2-hydroxy-3-methylpentanoic acid is a valeric acid derivative having an (R)-hydroxy substituent at the 2-position and an (S)-methyl substituent at the 3-position; one of 4 steroisomers of 2-hydroxy-3-methylpentanoic acid, generated by isoleucine metabolism. Found at significantly higher levels than normal in patients with maple syrup urine disease (MSUD). It is a (2R)-2-hydroxy monocarboxylic acid and a 2-hydroxy-3-methylpentanoic acid. It is functionally related to a valeric acid. It is a conjugate acid of a (2R,3S)-2-hydroxy-3-methylpentanoate.