FOR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2
- Product Name
- FOR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2
- CAS No.
- 1217449-28-9
- Chemical Name
- FOR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2
- Synonyms
- FORMYL-TRIPTORELIN (2-10);Formyl-(D-Trp?)-LHRH (2-10);FORMYL-(D-TRP6)-LHRH (2-10);FORMYL-[D-TRP6]-LH-RH FRAGMENT 2-10;FOR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2;FORMYL-(D-TRP6)-GONADOTROPIN-RELEASING HORMONE (2-10);FORMYL-(D-TRP6)-LUTEINIZING HORMONE-RELEASING FACTOR (2-10);FORMYL-(D-TRP6)-LUTEINIZING HORMONE-RELEASING HORMONE (2-10)
- CBNumber
- CB3236585
- Molecular Formula
- C60H77N17O12
- Formula Weight
- 1228.36
- MOL File
- Mol file
FOR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 Property
- Density
- 1.49±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- pka
- 9.82±0.15(Predicted)
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- PEP0003957
- Product name
- FORMYL-[D-TRP6]-LH-RH FRAGMENT 2-10
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $773.13
- Updated
- 2021/12/16
FOR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 Chemical Properties,Usage,Production
Biological Activity
Formyl-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 (Formyl-[D-Trp6]-LH-RH Fragment 2-10) is a peptide from GnRH (gonadotropin-releasing hormone) agonist, triptorelin. GnRH (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism. Application of triptorelin suppresses premature LH surge in IVF (in vitro fertilization). Additionally, triptorelin-mediated ovarian suppression in premenopausal women, undergoing chemotherapy for breast cancer, decreases chances of chemotherapy-associated early menopause.
FOR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 Preparation Products And Raw materials
Raw materials
Preparation Products
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