ChemicalBook > CAS DataBase List > FOR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2

FOR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2

Product Name
FOR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2
CAS No.
1217449-28-9
Chemical Name
FOR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2
Synonyms
FORMYL-TRIPTORELIN (2-10);Formyl-(D-Trp?)-LHRH (2-10);FORMYL-(D-TRP6)-LHRH (2-10);FORMYL-[D-TRP6]-LH-RH FRAGMENT 2-10;FOR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2;FORMYL-(D-TRP6)-GONADOTROPIN-RELEASING HORMONE (2-10);FORMYL-(D-TRP6)-LUTEINIZING HORMONE-RELEASING FACTOR (2-10);FORMYL-(D-TRP6)-LUTEINIZING HORMONE-RELEASING HORMONE (2-10)
CBNumber
CB3236585
Molecular Formula
C60H77N17O12
Formula Weight
1228.36
MOL File
Mol file
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FOR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 Property

Density 
1.49±0.1 g/cm3(Predicted)
storage temp. 
−20°C
pka
9.82±0.15(Predicted)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
PEP0003957
Product name
FORMYL-[D-TRP6]-LH-RH FRAGMENT 2-10
Purity
95.00%
Packaging
1MG
Price
$773.13
Updated
2021/12/16
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FOR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 Chemical Properties,Usage,Production

Biological Activity

Formyl-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 (Formyl-[D-Trp6]-LH-RH Fragment 2-10) is a peptide from GnRH (gonadotropin-releasing hormone) agonist, triptorelin. GnRH (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism. Application of triptorelin suppresses premature LH surge in IVF (in vitro fertilization). Additionally, triptorelin-mediated ovarian suppression in premenopausal women, undergoing chemotherapy for breast cancer, decreases chances of chemotherapy-associated early menopause.

FOR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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FOR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 Suppliers

China 16 Switzerland 1 United States 2 Global 19
Riedel-de Haen AG
Tel
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Fax
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Country
United States
ProdList
6773
Advantage
87
Chem-Impex International, Inc.
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Country
United States
ProdList
6730
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64

1217449-28-9, FOR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2Related Search:

Triptorelin

  • FORMYL-TRIPTORELIN (2-10)
  • FORMYL-(D-TRP6)-GONADOTROPIN-RELEASING HORMONE (2-10)
  • FORMYL-(D-TRP6)-LHRH (2-10)
  • FORMYL-[D-TRP6]-LH-RH FRAGMENT 2-10
  • FORMYL-(D-TRP6)-LUTEINIZING HORMONE-RELEASING FACTOR (2-10)
  • FORMYL-(D-TRP6)-LUTEINIZING HORMONE-RELEASING HORMONE (2-10)
  • FOR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2
  • Formyl-(D-Trp?)-LHRH (2-10)
  • 1217449-28-9
  • C60H77N17O12