ChemicalBook > CAS DataBase List > Isowightenon

Isowightenon

Product Name
Isowightenon
CAS No.
68436-47-5
Chemical Name
Isowightenon
Synonyms
Isowigtheone;Isowighteone;Isowightenon;3'-Dimethylallylgenistein;4',5,7-Trihydroxy-3'-prenylisoflavone;4',5,7-Trihydroxy-3'-(3-methyl-2-butenyl)isoflavone;3'-(3-Methyl-2-butenyl)-4',5,7-trihydroxyisoflavone;4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-[4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-
CBNumber
CB32377396
Molecular Formula
C20H18O5
Formula Weight
338.35
MOL File
68436-47-5.mol
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Isowightenon Property

solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
powder
color 
Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
I918230
Product name
Isowighteone
Packaging
1mg
Price
$110
Updated
2021/12/16
Biosynth Carbosynth
Product number
FI138625
Product name
Isowighteone
Packaging
1mg
Price
$375
Updated
2021/12/16
AK Scientific
Product number
W1718
Product name
Isowighteone
Packaging
1mg
Price
$556
Updated
2021/12/16
Biosynth Carbosynth
Product number
FI138625
Product name
Isowighteone
Packaging
2mg
Price
$600
Updated
2021/12/16
Arctom
Product number
CFN97166
Product name
Isowighteone
Purity
≥98%
Packaging
5mg
Price
$398
Updated
2021/12/16
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Isowightenon Chemical Properties,Usage,Production

Uses

Isowighteone is a natural product derivative of Genistein (G350000). Genistein exhibits specific inhibitory activity against tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol.

Definition

ChEBI: Isowighteone is a member of the class of 7-hydroxyisoflavones that is isoflavone substituted by hydroxy groups at positions 5, 7 and 4' and a prenyl group at position 3'. It has been isolated from Ficus mucuso. It has a role as a plant metabolite. It is functionally related to an isoflavone.

target

Antifection

Isowightenon Preparation Products And Raw materials

Raw materials

Preparation Products

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68436-47-5, IsowightenonRelated Search:


  • 3'-(3-Methyl-2-butenyl)-4',5,7-trihydroxyisoflavone
  • 3'-Dimethylallylgenistein
  • 4',5,7-Trihydroxy-3'-(3-methyl-2-butenyl)isoflavone
  • 4',5,7-Trihydroxy-3'-prenylisoflavone
  • Isowightenon
  • Isowighteone
  • Isowigtheone
  • 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-[4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-
  • 68436-47-5