1-Phenyl-1H-pyrazol-3(2H)-one
- Product Name
- 1-Phenyl-1H-pyrazol-3(2H)-one
- CAS No.
- 1008-79-3
- Chemical Name
- 1-Phenyl-1H-pyrazol-3(2H)-one
- Synonyms
- 1-Phenyl-3(2H)-pyrazolone;2-phenyl-1H-pyrazol-5-one;1-Phenyl-5H-IMidazol-4-one;1-Phenyl-3-hydroxypyrazole;1-Phenyl-1H-pyrazol-3(2H)-one;1-Phenyl-1,2-dihydropyrazol-3-one;1,2-Dihydro-1-phenyl-3H-pyrazol-3-one;3H-Pyrazol-3-one,1,2-dihydro-1-phenyl-;1-phenyl-1,5-dihydro-4H-iMidazol-4-one
- CBNumber
- CB32380709
- Molecular Formula
- C9H8N2O
- Formula Weight
- 160.17
- MOL File
- 1008-79-3.mol
1-Phenyl-1H-pyrazol-3(2H)-one Property
- Melting point:
- 154°C
- Boiling point:
- 286.07°C (rough estimate)
- Density
- 1.1846 (rough estimate)
- refractive index
- 1.5570 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 8.14±0.70(Predicted)
- Appearance
- Light brown to khaki Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P336465
- Product name
- 1-Phenyl-1H-pyrazol-3(2H)-one
- Packaging
- 50mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- P336465
- Product name
- 1-Phenyl-1H-pyrazol-3(2H)-one
- Packaging
- 100mg
- Price
- $265
- Updated
- 2021/12/16
- Product number
- A141645
- Product name
- 1-Phenyl-1H-pyrazol-3(2H)-one
- Purity
- 97%
- Packaging
- 100mg
- Price
- $66
- Updated
- 2021/12/16
- Product number
- A141645
- Product name
- 1-Phenyl-1H-pyrazol-3(2H)-one
- Purity
- 97%
- Packaging
- 250mg
- Price
- $106
- Updated
- 2021/12/16
- Product number
- CM133085
- Product name
- 1-phenyl-1,2-dihydro-3H-pyrazol-3-one
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $186
- Updated
- 2021/12/16
1-Phenyl-1H-pyrazol-3(2H)-one Chemical Properties,Usage,Production
Synthesis
92-43-3
1008-79-3
General procedure for the synthesis of 1-phenyl-1H-pyrazol-3(2H)-one from phenanthrone: 1-phenylpyrrolidin-3-one (82.99 mmol, 1.0 eq.) was dissolved in 5% aqueous sodium hydroxide solution and iron chloride hexahydrate (16.60 mmol, 0.2 eq.) was added. The reaction system was kept at 80 °C under oxygen atmosphere. After completion of the reaction, water was added to the reaction mixture to quench the reaction and the pH was adjusted with hydrochloric acid to 1~2. The reaction mixture was extracted with ethyl acetate and the organic layer was washed with saturated sodium chloride solution and dried over anhydrous sodium sulfate. The organic phase was concentrated under reduced pressure and the residue was purified by column chromatography (eluent ratio: petroleum ether:ethyl acetate = 2:1) to afford the light yellow solid product 1-phenyl-1H-pyrazol-3-ol (1.46 g, 11% yield).
References
[1] European Journal of Organic Chemistry, 2011, # 27, p. 5323 - 5330
[2] Tetrahedron, 2009, vol. 65, # 37, p. 7817 - 7824
[3] Dyes and Pigments, 2010, vol. 85, # 3, p. 79 - 85
[4] Bulletin of the Korean Chemical Society, 2010, vol. 31, # 11, p. 3341 - 3347
[5] Journal of Chemical Research, 2015, vol. 39, # 10, p. 594 - 600
1-Phenyl-1H-pyrazol-3(2H)-one Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-Phenyl-1H-pyrazol-3(2H)-one manufacturers
- Product
- 1-Phenyl-1H-pyrazol-3(2H)-one 1008-79-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000KG
- Release date
- 2024-07-30