1,3,4,6,7,11b-Hexahydro-2H-pyrazino[2,1-a]isoquinoline

Product Name: 1,3,4,6,7,11b-Hexahydro-2H-pyrazino[2,1-a]isoquinoline
CAS No.: 5234-86-6
Chemical Name: 1,3,4,6,7,11b-Hexahydro-2H-pyrazino[2,1-a]isoquinoline
Synonyms: Azaquinzole;1,3,4,6,7,11b-Hexahydro-2H-pyrazino[2,1-a]isoquinoline;2,3,4,6,7,11B-HEXAHYDRO-1H-PYRAZINO[2,1-A]ISOQUINOLINE;2H-Pyrazino[2,1-a]isoquinoline, 1,3,4,6,7,11bhexahydro-
CBNumber: CB32389373
Molecular Formula: C12H16N2
Formula Weight: 188.27
MOL File: 5234-86-6.mol

More

Less

1,3,4,6,7,11b-Hexahydro-2H-pyrazino[2,1-a]isoquinoline Property

storage temp.: Keep in dark place,Inert atmosphere,Room temperature

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

TRC

Product number: H949998
Product name: 2,3,4,6,7,11b-Hexahydro-1H-pyrazino[2,1-a]isoquinoline
Packaging: 50mg
Price: $200
Updated: 2021/12/16

AK Scientific

Product number: 7379AB
Product name: 2,3,4,6,7,11b-Hexahydro-1H-pyrazino[2,1-a]isoquinoline
Packaging: 250mg
Price: $436
Updated: 2021/12/16

Matrix Scientific

Product number: 178037
Product name: 1,3,4,6,7,11b-Hexahydro-2H-pyrazino[2,1-a]isoquinoline dihydrochloride
Packaging: 0.500g
Price: $480
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0149309
Product name: 2,3,4,6,7,11B-HEXAHYDRO-1H-PYRAZINO(2,1-A)ISOQUINOLINE
Purity: 95.00%
Packaging: 5MG
Price: $495.54
Updated: 2021/12/16

Matrix Scientific

Product number: 178037
Product name: 1,3,4,6,7,11b-Hexahydro-2H-pyrazino[2,1-a]isoquinoline dihydrochloride
Packaging: 1g
Price: $600
Updated: 2021/12/16

More

Less

1,3,4,6,7,11b-Hexahydro-2H-pyrazino[2,1-a]isoquinoline Chemical Properties,Usage,Production

Originator

Azaquinzole,Onbio Inc.

Manufacturing Process

2 Methods of producing of 1,2,3,6,7,11b-hexahydro-4H-pyrazino-[2,1- a]isoquinoline:
1). 214.0 g diethyl ester of oxalic acid are mixed with a solution of 238.0 g 1- aminomethyl-1,2,3,4-tetrahydroisoquinoline in 200 ml alcohol are boiled for 7 h. After cooling, the obtained crystals of 1,2,3,6,7,11b-hexahydro-4Hpyrazino[ 2,1-a]isoquinoline-3,4-dione are vacuum-filtered and washed with acetone and dried, melting point 220°C. Yield: 240.0 g.
55.0 g lithium aluminum hydride are dissolved in 650 ml absolute tetrahydrofuran and mixed dropwise with a suspension of 120.0 g 1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline-3,4-dione in 300 ml absolute tetrahydrofuran. After 7 h of boiling, the residual hydride is decomposed by the addition of water, and the reaction solution is worked up. The obtained 1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline is distilled in vacuum, boiling point 98°-100°C/0.01 mm. Yield: 86.0 g.
2). 16.2 g 1-aminomethyl-1,2,3,4-tetrahydroisoquinoline and 18.7 g ethylene dibromide are boiled for 4 h in n-butanol, with the addition of 13.8 g potassium carbonate. After the solvent is evaporated, the residue is treated with water, mixed with sodium hydroxide solution, and shaken out with chloroform. The chloroform solution is dried, concentrated by evaporation, and the resulting 1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline is distilled at 98°-100°C/0.01 mm. The yield amounts to 7.5 g.

Therapeutic Function

CNS depressant

1,3,4,6,7,11b-Hexahydro-2H-pyrazino[2,1-a]isoquinoline Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1,3,4,6,7,11b-Hexahydro-2H-pyrazino[2,1-a]isoquinoline Suppliers

China 18 India 1 United States 4 Global 23

SynAsst Chemical.

Tel: 021-60343070
Fax: 021-35122006
Country: China
ProdList: 12740
Advantage: 55

Shanghai Brain Biotechnology Co., Ltd.

Tel: 13564638271
Fax: 021-68948280
Email: shhjiang1977@163.com
Country: China
ProdList: 2987
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27313
Advantage: 60

BioPharmaMatrix,Inc.

Tel: 0510-86010668
Fax: 0510-86010668
Email: sales@biopharmamatrix.com
Country: China
ProdList: 4262
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Chengdu Novel Biomedical Co., Ltd.

Tel: 028-85255396 18302801538
Fax: 028-85255396
Email: cdnovell@163.com
Country: China
ProdList: 2323
Advantage: 58

Aikon International Limited

Tel: 025-66113011 18112977050
Fax: (5)02557626880
Email: cb6@aikonchem.com
Country: China
ProdList: 15494
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52693
Advantage: 58

Nanjing Easichem Co. ltd.

Tel: 18061688856
Email: easichem@126.com
Country: China
ProdList: 477
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

5234-86-6, 1,3,4,6,7,11b-Hexahydro-2H-pyrazino[2,1-a]isoquinolineRelated Search:

1,3,4,6,7,11b-Hexahydro-2H-pyrazino[2,1-a]isoquinoline

Azaquinzole

2,3,4,6,7,11B-HEXAHYDRO-1H-PYRAZINO[2,1-A]ISOQUINOLINE

2H-Pyrazino[2,1-a]isoquinoline, 1,3,4,6,7,11bhexahydro-

5234-86-6