(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one

Product Name: (3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one
CAS No.: 957-66-4
Chemical Name: (3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one
Synonyms: Isolinderalactone;Reaxys ID: 5276986;3,4-b']difuran-2(3H)-one;Isolinderalactone, 10 mM in DMSO;(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b;(3aS)-4β-Vinyl-3a,4,5,8bβ-tetrahydro-4,8-dimethyl-3-methylenebenzo[1,2-b:3,4-b']difuran-2(3H)-one;(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b]difuran-2(3H)-one;(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one;(3aS,4R,8bR)-4,8-Dimethyl-3-methylene-4-vinyl-3a,4,5,8b-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one;Benzo[1,2-b:3,4-b']difuran-2(3H)-one, 4-ethenyl-3a,4,5,8b-tetrahydro-4,8-dimethyl-3-methylene-, (3aS,4R,8bR)-
CBNumber: CB32424359
Molecular Formula: C15H16O3
Formula Weight: 244.29
MOL File: 957-66-4.mol

More

Less

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one Property

Melting point:: 118-121℃
Boiling point:: 378.8±42.0 °C(Predicted)
Density: 1.16±0.1 g/cm3 (20 ºC 760 Torr)
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Powder
color: White to off-white

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Usbiological

Product number: 300486
Product name: Isolinderalactone
Packaging: 20mg
Price: $509
Updated: 2021/12/16

AvaChem

Product number: 4262
Product name: Isolinderalactone
Packaging: 20mg
Price: $690
Updated: 2021/12/16

AvaChem

Product number: 4262
Product name: Isolinderalactone
Packaging: 1mg
Price: $119
Updated: 2021/12/16

Arctom

Product number: CFN99762
Product name: Isolinderalactone
Packaging: 5mg
Price: $238
Updated: 2021/12/16

DC Chemicals

Product number: DCZ-124
Product name: Isolinderalactone
Purity: >98%
Packaging: 20mg
Price: $280
Updated: 2021/12/16

More

Less

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one Chemical Properties,Usage,Production

Chemical Properties

Off-white needle-like crystals, soluble in methanol, ethanol, DMSO and other organic solvents, from Camphoraceae (Lauraceae) Uva Ursi Lindera strychnifolia Vill. root fine trace Neolitsea aciculata Koidz. root, trunk NANRENSHAN NEW WOOD JIANG ZI Neolitsea Roots of Neolitsea villosa (Blume) Merr.

Uses

Isolinderalactone suppresses human glioblastoma growth and angiogenic activity through the inhibition of VEGFR2 activation in endothelial cells[1]. Isolinderalactone suppresses the expression of B-cell lymphoma 2 (Bcl-2), survi

Definition

ChEBI: Isolinderalactone is a member of benzofurans. It has a role as a metabolite.

IC 50

VEGFR2; Bcl-2

References

[1] Park JH, et al. Isolinderalactone suppresses human glioblastoma growth and angiogenic activity in 3D microfluidic chip and in vivo mouse models.?Cancer Lett. 2020;478:71-81. DOI:10.1016/j.canlet.2020.03.009
[2] Hwang JY, et al. Isolinderalactone regulates the BCL-2/caspase-3/PARP pathway and suppresses tumor growth in a human glioblastoma multiforme xenograft mouse model.?Cancer Lett. 2019;443:25-33. DOI:10.1016/j.canlet.2018.11.027

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one Suppliers

China 76 United States 7 Global 83

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3988
Advantage: 66

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
Advantage: 60

Wuhan ChemFaces Biochemical Co., Ltd.

Tel: 18607101326 15172504745
Fax: +86-27-84254680
Email: aileen@chemfaces.com
Country: China
ProdList: 6905
Advantage: 55

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Shanghai Uteam Biotechnology Co., Ltd.

Tel: 021-36031160 13311776681
Email: 3338195766@QQ.com
Country: China
ProdList: 5093
Advantage: 55

More

Less

View Lastest Price from (3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Isolinderalactone 957-66-4
Price: US $0.00/mg
Min. Order: 20mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-05-07

957-66-4, (3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-oneRelated Search:

3-Methyl-1-butanol Polycaprolactone

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one

(3aS)-4β-Vinyl-3a,4,5,8bβ-tetrahydro-4,8-dimethyl-3-methylenebenzo[1,2-b:3,4-b']difuran-2(3H)-one

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b

3,4-b']difuran-2(3H)-one

Isolinderalactone

Reaxys ID: 5276986

Benzo[1,2-b:3,4-b']difuran-2(3H)-one, 4-ethenyl-3a,4,5,8b-tetrahydro-4,8-dimethyl-3-methylene-, (3aS,4R,8bR)-

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b]difuran-2(3H)-one

(3aS,4R,8bR)-4,8-Dimethyl-3-methylene-4-vinyl-3a,4,5,8b-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one

Survivin,VEGFR,Isolinderalactone,Vascular endothelial growth factor receptor,Inhibitor,IAP,Bcl-2 Family,inhibit

(3aS,4R,8bR)-4,8-Dimethyl-3-methylene-4-vinyl-3a,4,5,8b-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one , Isolinderalactone

Isolinderalactone, 10 mM in DMSO

957-66-4

Sesquiterpenoids