1,2-Diamino-3-chlorobenzene
- Product Name
- 1,2-Diamino-3-chlorobenzene
- CAS No.
- 21745-41-5
- Chemical Name
- 1,2-Diamino-3-chlorobenzene
- Synonyms
- 2-Amino-3-chloroaniline;6-Chloro-1,2-benzenediamine;3-Chloro-o-phenylenediamine;3-Chloro-1,2-benzenediamine;1,2-Diamino-3-chlorobenzene;3-Chlorobenzene-1,2-diamine;1,2-BenzenediaMine, 3-chloro-;(2-amino-3-chlorophenyl)amine(SALTDATA: FREE);3-Chloro-1,2-diaminobenzene, 3-Chlorophenylene-1,2-diamine;3-Chloro-1,2-diaminobenzene, 3-Chlorophenylene-1,2-diamine, 2,3-Diaminochlorobenzene
- CBNumber
- CB32442063
- Molecular Formula
- C6H7ClN2
- Formula Weight
- 142.59
- MOL File
- 21745-41-5.mol
1,2-Diamino-3-chlorobenzene Property
- Melting point:
- 27-29°
- Boiling point:
- 125 °C
- Density
- 1.345±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- SMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 3.10±0.10(Predicted)
- color
- Dark Brown to Black
Safety
- HS Code
- 2921511990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H227Combustible liquid
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C363535
- Product name
- 3-Chlorobenzene-1,2-diamine
- Packaging
- 10g
- Price
- $110
- Updated
- 2021/12/16
- Product number
- J94650
- Product name
- 1,2-Diamino-3-chlorobenzene
- Packaging
- 10g
- Price
- $140
- Updated
- 2021/12/16
- Product number
- 3630-5-Y2
- Product name
- 3-Chlorobenzene-1,2-diamine
- Purity
- 97%
- Packaging
- 5G
- Price
- $141
- Updated
- 2021/12/16
- Product number
- 076522
- Product name
- 1,2-Diamino-3-chlorobenzene
- Purity
- 95+%
- Packaging
- 5g
- Price
- $174
- Updated
- 2021/12/16
- Product number
- FC140243
- Product name
- 3-Chlorobenzene-1,2-diamine
- Packaging
- 5G
- Price
- $201
- Updated
- 2021/12/16
1,2-Diamino-3-chlorobenzene Chemical Properties,Usage,Production
Uses
3-Chlorobenzene-1,2-diamine is used as a reagent for electrochemical research or as a material for the preparation of foams.
Synthesis
59483-54-4
21745-41-5
Step 1: 3-chloro-2-nitroaniline (5.0 g, 29 mmol), zinc powder (18.9 g, 290 mmol) and ammonium chloride (31.0 g, 579 mmol) were stirred in 100 mL of a 1:1 ethanol-water mixture for 18 hours at room temperature. After completion of the reaction, the reaction mixture was filtered and the filtrate was concentrated to give a brown solid. The solid was transferred to a partition funnel and partitioned with dichloromethane and water. The organic layer was separated, the organic extracts were combined, dried with anhydrous magnesium sulfate, filtered and the solvent was removed in vacuum to give 3-chlorobenzene-1,2-diamine (4.00 g, 97% yield) as a brown solid.
References
[1] Journal of Medicinal Chemistry, 2010, vol. 53, # 3, p. 1357 - 1369
[2] Patent: US2010/120778, 2010, A1. Location in patent: Page/Page column 29
[3] Patent: WO2008/118468, 2008, A1. Location in patent: Page/Page column 132
[4] Patent: WO2009/134750, 2009, A1. Location in patent: Page/Page column 72
[5] ACS Medicinal Chemistry Letters, 2017, vol. 8, # 5, p. 543 - 548
1,2-Diamino-3-chlorobenzene Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1,2-Diamino-3-chlorobenzene manufacturers
- Product
- 1,2-Diamino-3-chlorobenzene 21745-41-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-11