IOMAZENIL

Product Name: IOMAZENIL
CAS No.: 127985-21-1
Chemical Name: IOMAZENIL
Synonyms: Iomazenil >=98% (HPLC);Ethyl 7-iodo-5,6-dihydro-5-methyl-6-oxo-4H-midazo[1,5-a][1,4]benzodiazepine-3-carboxylate;4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 5,6-dihydro-7-iodo-5-methyl-6-oxo-, ethyl ester
CBNumber: CB32446490
Molecular Formula: C15H14IN3O3
Formula Weight: 411.19
MOL File: 127985-21-1.mol

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IOMAZENIL Property

Boiling point:: 587.7±50.0 °C(Predicted)
Density: 1.77±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: soluble5mg/mL, clear (warmed)
form: powder
pka: 0.72±0.20(Predicted)
color: white to beige

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0645
Product name: Iomazenil
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $173
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML0645
Product name: Iomazenil
Purity: ≥98% (HPLC)
Packaging: 50mg
Price: $672
Updated: 2022/05/15

American Custom Chemicals Corporation

Product number: API0024879
Product name: IOMAZENIL
Purity: 95.00%
Packaging: 5MG
Price: $800.46
Updated: 2021/12/16

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IOMAZENIL Chemical Properties,Usage,Production

Uses

Iomazenil is a benzodiazepine receptor antagonist with partial inverse agonist activity. Iomazenil can assess the binding potential of central benzodiazepine receptors in the cerebral cortex and may reflect neuronal function in viable tissue. Iomazenil use is associated with improved cognitive function in adult patients with ischemic cerebral pathology after indirect revascularization surgery. Iomazenil demonstrated restoration of benzodiazepine receptor binding potential in the affected hemisphere after surgery on brain SPECT imaging[1].

Biological Activity

Iomazenil (Ro 16–0154) is a benzodiazepine competitive antagonist and partial inverse agonist. Iomazenil has been shown to counteract the effects of alcohol.

References

[1] Recovery of Cortical Neurotransmitter Receptor Function and Its Impact on Cognitive Improvement after Indirect Revascularization Surgery Alone for Adult Patients with Ischemic Moyamoya Disease: 123I-Iomazenil Single-Photon Emission Computed Tomography Study DOI:10.1016/j.wneu.2022.05.118

IOMAZENIL Preparation Products And Raw materials

Raw materials

Preparation Products

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IOMAZENIL Suppliers

China 6 United States 3 Global 9

TargetMol Chemicals Inc.

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Energy Chemical

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Beijing Biocreative Technology Co., Ltd.

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TargetMol Chemicals Inc.

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Merck KGaA

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Biosynth Biological Technology (Suzhou) Co Ltd

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TargetMol Chemicals Inc.

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Email: marketing@targetmol.com
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Hangzhou MolCore BioPharmatech Co.,Ltd.

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127985-21-1, IOMAZENILRelated Search:

2-(1H-IMIDAZOL-1-YL)BENZENECARBOXAMIDE IOMAZENIL 1,5-DIMETHYL-1H-IMIDAZOLE-4-CARBALDEHYDE 2-AMINO-6-IODOTOLUENE 2-IMIDAZOL-1-YL-BENZALDEHYDE 1-METHYL-1H-IMIDAZOLE-4-CARBOXYLIC ACID METHYL ESTER 1-[2-(1H-IMIDAZOL-1-YL)PHENYL]METHANAMINE 1-Methyl-1H-imidazole-4-carboxylic acid

Ethyl 7-iodo-5,6-dihydro-5-methyl-6-oxo-4H-midazo[1,5-a][1,4]benzodiazepine-3-carboxylate

4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 5,6-dihydro-7-iodo-5-methyl-6-oxo-, ethyl ester

Iomazenil >=98% (HPLC)

127985-21-1