ChemicalBook > CAS DataBase List > LIDORESTAT
LIDORESTAT
- Product Name
- LIDORESTAT
- CAS No.
- 245116-90-9
- Chemical Name
- LIDORESTAT
- Synonyms
- IDD-676;LIDORESTAT;LIDORESTATUM;(VOI)LIDORESTAT;3-[(4,5,7-Trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid;[3-(4,5,7-Trifluorobenzothiazol-2-ylmethyl)indol-1-yl]acetic acid;1H-Indole-1-aceticacid, 3-[(4,5,7-trifluoro-2-benzothiazolyl)methyl]-;2-(3-((4,5,7-TRIFLUOROBENZO[D]THIAZOL-2-YL)METHYL)-1H-INDOL-1-YL)ACETIC ACID
- CBNumber
- CB32448681
- Molecular Formula
- C18H11F3N2O2S
- Formula Weight
- 376.35
- MOL File
- 245116-90-9.mol
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LIDORESTAT Property
- Melting point:
- 177-178℃
- Boiling point:
- 591.4±50.0 °C(Predicted)
- Density
- 1.55
- form
- Solid
- pka
- 4.23±0.10(Predicted)
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0025212
- Product name
- Lidorestat
- Purity
- 99.50%
- Packaging
- 25mg
- Price
- $170
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0019191
- Product name
- LIDORESTAT
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.5
- Updated
- 2021/12/16
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LIDORESTAT Chemical Properties,Usage,Production
Uses
Treat ment of diabetic complications, including neuropathy, retinopathy, cataracts, nephropathy (selective aldose reductase inhibitor).
in vivo
Lidorestat (25 mg/kg/day; oral administration; twice daily; for 6 weeks; diabetic mice) treatment decreases fructose and reduces mortality in diabetic hAR-expressing mice. And Lidorestat does not affect weight[1].
| Animal Model: | Diabetic low-density lipoprotein (LDL) receptor-deficient [Ldlr(-/-)] mice[1] |
| Dosage: | 25 mg/kg/day |
| Administration: | Oral administration; twice daily; for 6 weeks |
| Result: | Diabetic hAR-expressing mice had decreased fructose and reduced mortality. |
LIDORESTAT Preparation Products And Raw materials
Raw materials
Preparation Products
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LIDORESTAT Suppliers
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