7-ISOPROPYLISATIN

Product Name
7-ISOPROPYLISATIN
CAS No.
57816-97-4
Chemical Name
7-ISOPROPYLISATIN
Synonyms
7-ISOPROPYLISATIN;UKRORGSYN-BB BBV-030970;7-Isopropylindoline-2,3-dione;7-(1-Methylethyl)-1H-indole-2,3-dione;1H-Indole-2,3-dione, 7-(1-methylethyl)-
CBNumber
CB32449855
Molecular Formula
C11H11NO2
Formula Weight
189.21
MOL File
57816-97-4.mol
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7-ISOPROPYLISATIN Property

Melting point:
196-198 °C(Solv: dichloromethane (75-09-2))
Density 
1.200±0.06 g/cm3(Predicted)
pka
9.81±0.20(Predicted)
InChI
InChI=1S/C11H11NO2/c1-6(2)7-4-3-5-8-9(7)12-11(14)10(8)13/h3-6H,1-2H3,(H,12,13,14)
InChIKey
XWJSENVAAAAHBN-UHFFFAOYSA-N
SMILES
N1C2=C(C=CC=C2C(C)C)C(=O)C1=O
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
I873468
Product name
7-Isopropyl-1H-indole-2,3-dione
Packaging
50mg
Price
$55
Updated
2021/12/16
TRC
Product number
I873468
Product name
7-Isopropyl-1H-indole-2,3-dione
Packaging
500mg
Price
$275
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0384086
Product name
7-ISOPROPYLISATIN
Purity
95.00%
Packaging
5MG
Price
$504.61
Updated
2021/12/16
AK Scientific
Product number
4708CT
Product name
7-Isopropylindoline-2,3-dione
Packaging
2.5g
Price
$853
Updated
2021/12/16
Matrix Scientific
Product number
177953
Product name
7-Isopropyl-1H-indole-2,3-dione
Packaging
0.500g
Price
$160
Updated
2021/12/16
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7-ISOPROPYLISATIN Chemical Properties,Usage,Production

Uses

7-Isopropyl-1H-indole-2,3-dione is used in the synthetic preparation of 2-aminoquinazoline derivatives as PLK1 inhibitor useful in treatment of various diseases.

Synthesis

To concentrated sulfuric acid at 80° C. was added 2-hydroxyimino-N-(2-isopropyl-phenyl)-acetamide in several small portions over 10 minutes. After addition it was heated at 80° C. for 30 minutes., then poured into ice. Filtration, washing with water, and drying under vacuum over P2O5 provided 2.974 g (84%) of 7-Isopropyl-1H-indole-2,3-dione as a solid. 

7-ISOPROPYLISATIN Preparation Products And Raw materials

Raw materials

Preparation Products

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7-ISOPROPYLISATIN Suppliers

Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Shanghai ChuangYan Chemical Technology Co., Ltd.
Tel
021-11111111 11111111111
Fax
qq:546919421
Email
546919421@qq.com
Country
China
ProdList
3217
Advantage
55
Aikon International Limited
Tel
025-66113011 18112977050
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
16027
Advantage
58
Shanghai WangFa Chemical Technology Co., Ltd.
Tel
13918479294
Fax
-
Email
xiebenfa@163.com
Country
China
ProdList
3506
Advantage
58
Changzhou Kechem Bio-Scientific Co., LTD.
Tel
0519-68985668 13685222090
Fax
qq735434464
Email
sales@kechem.cn
Country
China
ProdList
26028
Advantage
58
Hubei Co-prosperity Medicine Technonlogy Co., Ltd
Tel
2383948258 19172820304
Email
2383948258@qq.com
Country
China
ProdList
12987
Advantage
58
Hefei Mokai Pharmaceutical Technology Co., Ltd
Tel
18130062233
Email
3362556465@qq.com
Country
China
ProdList
7999
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
62075
Advantage
58
Heze Aiding Pharmaceutical Co., Ltd
Tel
17661365138
Email
2845578351@qq.com
Country
China
ProdList
7107
Advantage
58
Shanghai Jieshikai Biotechnology Co. , Ltd.
Tel
021-57520305 15221441005
Email
wangkang@jskchem.com
Country
China
ProdList
49234
Advantage
58

57816-97-4, 7-ISOPROPYLISATINRelated Search:


  • 7-ISOPROPYLISATIN
  • UKRORGSYN-BB BBV-030970
  • 1H-Indole-2,3-dione, 7-(1-methylethyl)-
  • 7-Isopropylindoline-2,3-dione
  • 7-(1-Methylethyl)-1H-indole-2,3-dione
  • 57816-97-4