OCTANOYL-DL-CARNITIN CHLORIDE Property

Melting point:

178-180°C

storage temp. 

-20°C Freezer, Under Inert Atmosphere

solubility 

Methanol (Slightly), Water (Slightly)

form 

Solid

color 

White

Stability:

Hygroscopic

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

OCTANOYL-DL-CARNITIN CHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A metabolite of Carnitine.

Biological Activity

(±)-octanoylcarnitine chloride is a homolog of acetylcarnitine chloride. acylcarnitines, the acetyl derivatives of carnitine, are important intermediates in lipid metabolism, required for the transport of long-chain fatty acids into mitochondria for β-oxidation and atp production, and for the removal of excess short-chain and medium-chain fatty acids. (±)-octanoylcarnitine has been shown to decrease the oxidation rate of the branched-chain 2-oxo acids 4-methyl-2-oxopentanoate and 3-methyl-2-oxobutanoate in isolated rat muscle mitochondria in the presence of carnitine, but octanoyl-l-carnitine increases oxidation of 4-methyl-2-oxopentanoate in the absence of carnitine. in addition, (±)-octanoylcarnitine, along with malate, has been used as a mitochondrial respiration substrate to evaluate the effect of creatine on the respiration rate of isolated rat cardiac fibers exposed to increasing concentrations of adp.1. zhang y, ma q, bai x. effects of dietary acetyl-l-carnitine on meat quality and lipid metabolism in arbor acres broilers. asian-australasian journal of animal sciences, 2010, 23(12): 1639-1644.2. veerkamp jh, van moerkerk ht, wagenmakers aj. interaction of short-chain and branched-chain fatty acids and their carnitine and coa esters and of various metabolites and agents with branched-chain 2-oxo acid oxidation in rat muscle and liver mitochondria. international journal of biochemistry, 1985, 17(9): 967-974.3. toleikis a, trumbeckaite s, liobikas j, et al. fatty acid oxidation and mitochondrial morphology changes as key modulators of the affinity for adp in rat heart mitochondria. cells, 2020, 9(2): 340.

storage

Desiccate at RT