ChemicalBook > CAS DataBase List > (+/-)-LY367385
(+/-)-LY367385
- Product Name
- (+/-)-LY367385
- CAS No.
- 198419-90-8
- Chemical Name
- (+/-)-LY367385
- Synonyms
- (+/-)-LY367385;LY 367385, (±)-;4-(AMINO-CARBOXY-METHYL)-3-METHYL-BENZOIC ACID;Benzeneacetic acid, α-amino-4-carboxy-2-methyl-;BENZENEACETIC ACID, A-AMINO-4-CARBOXY-2-METHYL-
- CBNumber
- CB32454095
- Molecular Formula
- C10H11NO4
- Formula Weight
- 209.2
- MOL File
- 198419-90-8.mol
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(+/-)-LY367385 Property
- Boiling point:
- 434.0±45.0 °C(Predicted)
- Density
- 1.393±0.06 g/cm3(Predicted)
- solubility
- Water: 20 mg/ml
- form
- A solid
- pka
- 1.72±0.10(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
TRC
- Product number
- L503210
- Product name
- (±)-LY367385
- Packaging
- 0.5mg
- Price
- $45
- Updated
- 2021/12/16
TRC
- Product number
- L503210
- Product name
- (±)-LY367385
- Packaging
- 1mg
- Price
- $60
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- BRS0000045
- Product name
- 4-(AMINO-CARBOXY-METHYL)-3-METHYL-BENZOIC ACID
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $223.65
- Updated
- 2021/12/16
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(+/-)-LY367385 Chemical Properties,Usage,Production
Description
(±)-LY367385 is an antagonist of metabotropic glutamate receptor 1α (mGluR1α).1 It inhibits phosphoinositide (PI) hydrolysis selectively in AV-12 cells expressing mGluR1α over those expressing mGluR5a (IC50s = 19 and >300 μM, respectively).
References
1. Salt, T.E., Jones, H.E., Copeland, C.S., et al. Function of mGlu1 receptors in the modulation of nociceptive processing in the thalamus Neuropharmacology 79(100),405-411(2014).
(+/-)-LY367385 Preparation Products And Raw materials
Raw materials
Preparation Products
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(+/-)-LY367385 Suppliers
198419-90-8, (+/-)-LY367385Related Search:
(1R)-1-AMINO-1,2,3,4-TETRAHYDRONAPHTHALENE-1,6-DICARBOXYLIC ACID
(1S)-1-AMINO-1,2,3,4-TETRAHYDRONAPHTHALENE-1,6-DICARBOXYLIC ACID
(+/-)-LY367385
LY 367385
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