1H-INDENE-2-BORONIC ACID PINACOL ESTER

Product Name: 1H-INDENE-2-BORONIC ACID PINACOL ESTER
CAS No.: 749869-98-5
Chemical Name: 1H-INDENE-2-BORONIC ACID PINACOL ESTER
Synonyms: 1H-Indene-2-boronic acid picol ester;1H-INDENE-2-BORONIC ACID PINACOL ESTER;1H-Indene-2-boronic acid pinacol ester 97%;1H-Indene-2-boronic acid pinacol ester;2-(1H-Inden-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;1,3,2-Dioxaborolane, 2-(1H-inden-2-yl)-4,4,5,5-tetramethyl-
CBNumber: CB32459409
Molecular Formula: C15H19BO2
Formula Weight: 242.12
MOL File: 749869-98-5.mol

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1H-INDENE-2-BORONIC ACID PINACOL ESTER Property

Melting point:: 72-80°C
Boiling point:: 293.4±50.0 °C(Predicted)
Density: 1.06±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
form: solid
Appearance: White to off-white Solid
InChI: 1S/C15H19BO2/c1-14(2)15(3,4)18-16(17-14)13-9-11-7-5-6-8-12(11)10-13/h5-9H,10H2,1-4H3
InChIKey: GHLNFPJNICWOHP-UHFFFAOYSA-N
SMILES: CC1(C)OB(OC1(C)C)C2=Cc3ccccc3C2

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Safety

WGK Germany: 3
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 766070
Product name: 1H-Indene-2-boronic acid pinacol ester
Purity: 97%
Packaging: 500mg
Price: $295
Updated: 2023/06/20

American Custom Chemicals Corporation

Product number: BOR0003289
Product name: 1H-INDENE-2-BORONIC ACID PINACOL ESTER
Purity: 96.00%
Packaging: 1G
Price: $190.05
Updated: 2021/12/16

Crysdot

Product number: CD12036729
Product name: 2-(1H-Inden-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Purity: 95+%
Packaging: 250mg
Price: $276
Updated: 2021/12/16

Chemenu

Product number: CM123749
Product name: 2-(1H-Inden-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Purity: 98%
Packaging: 1g
Price: $146
Updated: 2021/12/16

Crysdot

Product number: CD12036729
Product name: 2-(1H-Inden-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Purity: 95+%
Packaging: 1g
Price: $609
Updated: 2021/12/16

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1H-INDENE-2-BORONIC ACID PINACOL ESTER Chemical Properties,Usage,Production

Synthesis

10485-09-3

25015-63-8

749869-98-5

The general procedure for the synthesis of 2-(1H-inden-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolanes from 2-bromoindene and pinacolborane was carried out as follows: under nitrogen protection (PPh3)2PdCl2 (0.54 g, 0.77 mmol) and 2-bromoindene (4.98 g, 25.54 mmol) were added to a pre-oven-dried Schlenk flask followed by addition of dioxane (50 mL). Triethylamine (10.7 mL, 76.6 mmol) and pinacolborane (5.56 mL, 38.31 mmol) were added sequentially via syringe at room temperature (25 °C). The reaction mixture was stirred at 80 °C for 5.5 hours. After completion of the reaction, it was cooled to room temperature, the reaction was quenched with water and saturated saline (20 mL) was added. The organic layer was separated and the aqueous layer was extracted with ether (2 x 50 mL). The organic layers were combined, washed with brine, dried over anhydrous Na2SO4 and concentrated. Purification of the residue by Kugelrohr distillation gave the target product 2-(1H-inden-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane as a white solid (melting point 73-74 °C) in 69% yield. The product is stable in air and can be stored and handled.1H NMR (300 MHz, CDCl3) δ 7.58 (s, 1H), 7.50 (d, J = 7 Hz, 1H), 7.46 (d, J = 7 Hz, 1H), 7.30-7.21 (m, 2H), 3.54 (s, 2H), 1.33 (s, 12H); 13C NMR (75 MHz, CDCl3) δ 147.0, 145.7, 145.0, 126.3, 126.0, 124.0, 122.0, 83.6, 41.7, 25.1.

References

[1] Patent: WO2013/91837, 2013, A1. Location in patent: Page/Page column 20; 21
[2] Patent: WO2013/91836, 2013, A1. Location in patent: Page/Page column 20; 21

1H-INDENE-2-BORONIC ACID PINACOL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-INDENE-2-BORONIC ACID PINACOL ESTER Suppliers

China 27 United States 2 Global 29

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749869-98-5, 1H-INDENE-2-BORONIC ACID PINACOL ESTERRelated Search:

1H-INDENE-2-BORONIC ACID PINACOL ESTER

2-(1H-Inden-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

1H-Indene-2-boronic acid picol ester

1,3,2-Dioxaborolane, 2-(1H-inden-2-yl)-4,4,5,5-tetramethyl-

1H-Indene-2-boronic acid pinacol ester 97%

1<i>H</i>-Indene-2-boronic acid pinacol ester

749869-98-5