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CILANSETRON

Product Name
CILANSETRON
CAS No.
120635-47-4
Chemical Name
CILANSETRON
Synonyms
5-HT3 antagonist 3;Imidazol-1-yl compound 1;5 HT3 antagonist 3,5-HT-3 antagonist 3,5HT3 antagonist 3;10-((2-methyl-1H-imidazol-1-yl)methyl)-5,6,9,10-tetrahydro-4H-pyrido[3,2,1-jk]carbazol-11(8H)-one;4H-Pyrido[3,2,1-jk]carbazol-11(8H)-one, 5,6,9,10-tetrahydro-10-[(2-methyl-1H-imidazol-1-yl)methyl]-
CBNumber
CB32460601
Molecular Formula
C20H21N3O
Formula Weight
319.4
MOL File
120635-47-4.mol
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CILANSETRON Property

Boiling point:
600.6±50.0 °C(Predicted)
Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
7.50±0.33(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0009148
Product name
CILANSETRON
Purity
95.00%
Packaging
5MG
Price
$501.14
Updated
2021/12/16
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CILANSETRON Chemical Properties,Usage,Production

Uses

5-HT3 antagonist 3 (Compound 15b) is a high-affinity 5-HT3 receptor antagonist. 5-HT3 antagonist 3 binds to 5-HT3 receptors in rat brain cortical membranes with Ki of 0.25 nM[1].

IC 50

5-HT3 Receptor: 0.25 nM (Ki)

References

[1] van Wijngaarden I, et al. Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. J Med Chem. 1993 Nov 12;36(23):3693-9. DOI:10.1021/jm00075a026

CILANSETRON Preparation Products And Raw materials

Raw materials

Preparation Products

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CILANSETRON Suppliers

BOC Sciences
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1-631-485-4226; 16314854226
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United States
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MedChemexpress LLC
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021-58955995
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609-228-5909
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sales@medchemexpress.cn
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Xenoah Pharmaceutical Inc.
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0512-6956-1983
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info@xenoah.com
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China
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TargetMol Chemicals Inc.
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+1-781-999-5354; +17819995354
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marketing@targetmol.com
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United States
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Shanxi Xuanran Import and Export Trade Co., Ltd.
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TargetMol Chemicals Inc.
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Shanghai Yifei Biotechnology Co. , Ltd.
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Nanjing Shizhou Biology Technology Co.,Ltd
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120635-47-4, CILANSETRONRelated Search:


  • 4H-Pyrido[3,2,1-jk]carbazol-11(8H)-one, 5,6,9,10-tetrahydro-10-[(2-methyl-1H-imidazol-1-yl)methyl]-
  • 10-((2-methyl-1H-imidazol-1-yl)methyl)-5,6,9,10-tetrahydro-4H-pyrido[3,2,1-jk]carbazol-11(8H)-one
  • Imidazol-1-yl compound 1
  • 5-HT3 antagonist 3
  • 5 HT3 antagonist 3,5-HT-3 antagonist 3,5HT3 antagonist 3
  • 120635-47-4