7-BENZYL-5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE

Product Name: 7-BENZYL-5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE
CAS No.: 62459-02-3
Chemical Name: 7-BENZYL-5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE
Synonyms: 3H)-dione;7-benzyl-1H,3H,5H,6H,8H-pyrido[3,4-d]pyrimidine-2,4-dione;7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyriMidine-2,4-diol;7-benzyl-1,5,6,8-tetrahydropyrido[4,3-e]pyrimidine-2,4-dione;7-benzyl-1,5,6,8-tetrahydropyrido[3,4-d]pyrimidine-2,4-dione;7-benzyl-1H,2H,3H,4H,5H,6H,7H,8H-pyrido[3,4-d]pyriMidine-2,4-dione;7-BENZYL-5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE;7-BENZYL-5,6,7,8-TETRAHYDROPYRIDO[3,4-DJPYRIMIDINE-2,4(1H,3H)-DIONE;7-(phenylmethyl)-1,5,6,8-tetrahydropyrido[3,4-d]pyrimidine-2,4-dione;7-BENZYL-1,5,6,8-TETRAHYDROPYRIDO[4,3-E]PYRIMIDINE-2,4-DIONE 62459-02-3
CBNumber: CB32464311
Molecular Formula: C14H15N3O2
Formula Weight: 257.29
MOL File: 62459-02-3.mol

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7-BENZYL-5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE Property

Melting point:: 232 °C(Solv: acetone (67-64-1))
Density: 1.33±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 10.00±0.20(Predicted)
Appearance: White to off-white Solid
InChI: InChI=1S/C14H15N3O2/c18-13-11-6-7-17(8-10-4-2-1-3-5-10)9-12(11)15-14(19)16-13/h1-5H,6-9H2,(H2,15,16,18,19)
InChIKey: DYNBNPAECUWPPS-UHFFFAOYSA-N
SMILES: C1(=O)NC(=O)C2CCN(CC3=CC=CC=C3)CC=2N1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FB148742
Product name: 7-Benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione
Packaging: 25mg
Price: $56
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB148742
Product name: 7-Benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione
Packaging: 50mg
Price: $98
Updated: 2021/12/16

AK Scientific

Product number: W7449
Product name: 7-Benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione
Packaging: 250mg
Price: $150
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB148742
Product name: 7-Benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione
Packaging: 100mg
Price: $171
Updated: 2021/12/16

AK Scientific

Product number: W7449
Product name: 7-Benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione
Packaging: 1g
Price: $300
Updated: 2021/12/16

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7-BENZYL-5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE Chemical Properties,Usage,Production

Synthesis

39514-19-7

57-13-6

62459-02-3

To a solution of ethyl 1-benzyl-3-oxa-4-piperidinecarboxylate (12.0 g, 40.4 mmol) in methanol (200 ml) at 0 °C was added sequentially urea (5.1 g, 84.8 mmol) and sodium methanolate (12.3 g, 228 mmol). The reaction mixture was stirred at 60°C for 96 hours under nitrogen protection. After completion of the reaction, the mixture was cooled to room temperature and concentrated under reduced pressure to remove the solvent. The residue was purified by silica gel column chromatography (eluent: dichloromethane/methanol=10:1, v/v) to afford 7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione (6.3 g, 61% yield). lRMS (M+H+) m/z: calculated value 258.29; measured value 258.30.

References

[1] Patent: WO2014/15291, 2014, A1. Location in patent: Page/Page column 174; 175

7-BENZYL-5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE Preparation Products And Raw materials

Raw materials

Preparation Products

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7-BENZYL-5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE Suppliers

China 107 China Hong Kong 1 Germany 1 India 1 United Kingdom 1 United States 9 Global 120

Hotechem Shanghai Co., Ltd.,

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Nanjing Norris-Pharm Technology Co., Ltd

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View Lastest Price from 7-BENZYL-5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 7-BENZYL-5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE 62459-02-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-12

Career Henan Chemical Co

Product: 7-BENZYL-5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE 62459-02-3
Price: US $5.50/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 1kg-100kg
Release date: 2020-01-14

62459-02-3, 7-BENZYL-5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONERelated Search:

Tetryzoline 7-BENZYL-2,7-DIAZASPIRO[3.5]NONANE 7-BENZYL-5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE

7-BENZYL-5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE

3H)-dione

7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyriMidine-2,4-diol

7-benzyl-1H,2H,3H,4H,5H,6H,7H,8H-pyrido[3,4-d]pyriMidine-2,4-dione

7-benzyl-1,5,6,8-tetrahydropyrido[3,4-d]pyrimidine-2,4-dione

7-(phenylmethyl)-1,5,6,8-tetrahydropyrido[3,4-d]pyrimidine-2,4-dione

7-benzyl-1H,3H,5H,6H,8H-pyrido[3,4-d]pyrimidine-2,4-dione

rido[3,4-d]pyriMidine-2,4(1H,3H)-dione, 5,6,7,8-tetrahydro-7-(phenylMethyl)-

7-benzyl-1,5,6,8-tetrahydropyrido[4,3-e]pyrimidine-2,4-dione

Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione, 5,6,7,8-tetrahydro-7-(phenylmethyl)-

7-BENZYL-1,5,6,8-TETRAHYDROPYRIDO[4,3-E]PYRIMIDINE-2,4-DIONE 62459-02-3

7-BENZYL-5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE ISO 9001：2015 REACH

7-BENZYL-5,6,7,8-TETRAHYDROPYRIDO[3,4-DJPYRIMIDINE-2,4(1H,3H)-DIONE

62459-02-3

pyrimidine

Heterocycle-Pyrimidine series