5-BROMO-2,3-DIMETHYLPYRIDINE
Uses- Product Name
- 5-BROMO-2,3-DIMETHYLPYRIDINE
- CAS No.
- 27063-90-7
- Chemical Name
- 5-BROMO-2,3-DIMETHYLPYRIDINE
- Synonyms
- 3-DIMETHYLPYRIDINE;5-Bromo-2,3-lutidine;3-broMo-5,6-diMethylpyridine;2,3-DiMethyl-5-broMopyridine;5-BROMO-2,3-DIMETHYLPYRIDINE;Pyridine, 5-bromo-2,3-dimethyl-;5-BROMO-2,3-DIMETHYLPYRIDINE ISO 9001：2015 REACH
- CBNumber
- CB32464997
- Molecular Formula
- C7H8BrN
- Formula Weight
- 186.05
- MOL File
- 27063-90-7.mol
5-BROMO-2,3-DIMETHYLPYRIDINE Property
- Boiling point:
- 40℃ (40 Torr)
- Density
- 1.415±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 3.89±0.20(Predicted)
- form
- liquid
- color
- Clear, almost colourless
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B691773
- Product name
- 5-Bromo-2,3-dimethylpyridine
- Packaging
- 25mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR46088
- Product name
- 5-Bromo-2,3-dimethylpyridine
- Packaging
- 250mg
- Price
- $98
- Updated
- 2021/12/16
- Product number
- FB55778
- Product name
- 5-Bromo-2,3-dimethylpyridine
- Packaging
- 250mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- 3H32-9-5K
- Product name
- 5-Bromo-2,3-dimethylpyridine
- Packaging
- 250mg
- Price
- $108
- Updated
- 2021/12/16
- Product number
- W5017
- Product name
- 5-Bromo-2,3-dimethylpyridine
- Packaging
- 10g
- Price
- $134
- Updated
- 2021/12/16
5-BROMO-2,3-DIMETHYLPYRIDINE Chemical Properties,Usage,Production
Uses
2,3-Dimethyl-5-bromopyridine is an organic intermediate that can be prepared in one step from 2,3-dimethylpyridine. It can be used as a pharmaceutical intermediate.
Synthesis
583-61-9
27063-90-7
Step 1. Synthesis of 5-bromo-2,3-dimethylpyridine In a round-bottomed flask fitted with a water-cooled reflux condenser and a calcium chloride drying tube, 2,3-dimethylpyridine (6.79 mL, 60 mmol) was dissolved in fuming sulfuric acid (80 mL) and the reaction temperature was maintained at 150°C. The reaction temperature was kept at 150°C. Bromine (3.1 mL, 60 mmol) was added slowly and dropwise over a period of 2 hours. The reaction mixture took on a deep red color and after continued stirring for 16 hours, it was cooled to room temperature and allowed to stand overnight. The reaction mixture was carefully poured into about 400 g of ice and adjusted to pH 12 with base under cooling in an ice bath.The aqueous phase was extracted with ether and the organic phases were combined, washed with brine and dried over anhydrous magnesium sulfate. The solvent was removed by concentration under reduced pressure and the residue was purified by silica gel column chromatography (50 g silica gel, eluent 2-20% ethyl acetate in hexane solution) to give 2,3-dimethyl-5-bromopyridine (8.3 g) as a colorless oil.
References
[1] Patent: US2014/194386, 2014, A1. Location in patent: Paragraph 0520
5-BROMO-2,3-DIMETHYLPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-BROMO-2,3-DIMETHYLPYRIDINE manufacturers
- Product
- 5-BROMO-2,3-DIMETHYLPYRIDINE 27063-90-7
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-03-11
- Product
- 5-BROMO-2,3-DIMETHYLPYRIDINE 27063-90-7
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-23
- Product
- 2,3-Dimethyl-5-bromopyridine 27063-90-7
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 500 MT
- Release date
- 2020-05-12