ChemicalBook > CAS DataBase List > 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE

2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE

Product Name
2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
CAS No.
14665-75-9
Chemical Name
2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
Synonyms
Phenylephrine Impurity 26;2-AMino-3'-hydroxy-acetophenone HCl;2-amino-1-(3-hydroxy-phenyl)-ethanone;2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE;2-Amino-1-(3-hydroxyphenyl)ethanone Hydrochloride
CBNumber
CB32467130
Molecular Formula
C8H9NO2.ClH
Formula Weight
187.625
MOL File
14665-75-9.mol
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2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE Property

Melting point:
221–222°C
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form 
Solid
color 
Pale Beige to Brown
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A611325
Product name
2-Amino-3’-hydroxy-acetophenoneHydrochloride
Packaging
100mg
Price
$655
Updated
2021/12/16
TRC
Product number
A611325
Product name
2-Amino-3’-hydroxy-acetophenoneHydrochloride
Packaging
250mg
Price
$1500
Updated
2021/12/16
Acrotein
Product number
AM-0114
Product name
2-Amino-3'-hydroxy-acetophenoneHCl
Purity
97%
Packaging
0.5g
Price
$119.17
Updated
2021/12/16
Acrotein
Product number
AM-0114
Product name
2-Amino-3'-hydroxy-acetophenoneHCl
Purity
97%
Packaging
5g
Price
$586.67
Updated
2021/12/16
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2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

2-Amino-3’-hydroxy-acetophenone Hydrochloride is a reactant in the synthesis of TRPM8 modulators.

Preparation

Preparation by hydrolysis of m-(benzoyloxy)- a-amino-acetophenone hydrochloride (SM) (m.p. 202–205°) with refluxing 10% hydrochloric acid (quantitative yield), for 2 h (80%); ? with 37% hydrochloric acid in chlorobenzene at 90° for 3 h (90%). SM was obtained by reaction of hexamethylenetetramine with m-(benzoyloxy)- a-bromoacetophenone (m.p. 162°) in ethanol in the presence of 37% hydrochloric acid for 6 h at r.t. (75%).

2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE Suppliers

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